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January - April 1999

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• Cover (HTML Version for viewing)
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Editorial

• First Anniversary of the First Electronic Peer-Reviewed Pharmaceutical Sciences Journal
  Fakhreddin Jamali
  PDF Version for printing, page 1

Views

• Pharmacokinetic Tricks and Traps: Drug Dosage Adjustment in Renal Failure (HTML Version for viewing)
  Relating drug clearance to creatinine clearance.
  Harold Boxenbaum
  PDF Version for printing, page 2

Reviews

• Sustained Release and Enteric Coated NSAIDs: Are They Really GI Safe? (HTML Version for viewing)
  Modified release NSAIDs and the GI tract.
  Neal M. Davies
  PDF Version for printing, page 5

Original Articles

• Are the current bioequivalence standards sufficient for the acceptance of narrow therapeutic index drugs? Utilization of a computer simulated warfarin bioequivalence model. (HTML Version for viewing)
  A computer simulation to determine the likelihood of two bioequivalent generic warfarin formulations passing current bioequivalence criteria against each other at varying bioavailability.
  Scott E. Walker and Mark H. Friesen
  PDF Version for printing, page 15
• Disposition of ethopropazine enantiomers in the rat: Tissue distribution and plasma protein binding. (HTML Version for viewing)
  Determining the in vitro plasma protein binding, and the in vivo brain, heart and plasma concentrations of ET enantiomers in the rate after iv doses.
  Dion R. Brocks and Mojdeh Maboudian-Esfahani
  PDF Version for printing, page 23
• Methoxyflurane Anesthesia Augments The Chronotropic And Dromotropic Effects Of Verapamil. (HTML Version for viewing)
  Assessing the effects of anesthesia with MF on the dromotropic and chronotropic effects of VER in the rat.
  Patrick R. Mayo and Fakhreddin Jamali
  PDF Version for printing, page 30

Departments (HTML Versions for viewing)
Call for Papers
Editorial Board
Editorial Staff
Index
Submission Guidelines
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Published by the Canadian Society for Pharmaceutical Sciences
Copyright © 1998 by the Canadian Society for Pharmaceutical Sciences.
http://www.ualberta.ca/~csps