Current research activity in Uludag group is comprised of two avenues of explorations, as described below. There are significant overlaps in working philosophy in research themes, and the activity in each focus typically complements other research avenues.
Bone Regeneration
The first area of focus involves regeneration of bone tissue using protein-based growth factors. Our goal is to develop engineered nanoparticles and bone-targeting technologies that can effectively deliver the proteins to sites of bone induction. Regenerative mechanisms inherent in bone tissues are ultimately stimulated for new bone tissue deposition. » read more
Non-viral Gene Delivery
The second area of focus involves design of polymeric biomaterials for delivery of nucleic acid-based therapeutics. These therapeutic agents include plasmid DNA molecules with functional genes, and gene-silencing siRNA molecules. Amphiphilic polymers are engineered from cationic and lipophilic groups so as to deliver the nucleic acids to clinically-relevant cells. » read more
Collaboration
Our research endeavour is highly collaborative in nature. At times, we lend our expertise to other researchers by sharing our tools and materials for the purposes of their projects. At other times, joint projects are executed with other investigators to accomplish specific research goals. » read more
Acknowledgement
The projects in Uludag lab are primarily funded by operating grants from the Canadian Institutes of Health Research and Natural Sciences (CIHR) and Engineering Research Council of Canada (NSERC). » read more
Lab Ad in Department Brochure
View articles of our research and personnel in the Chemical and Materials Engineering department brochure.. » read more
