Selected publications
"Direct measurement of the full, sequence-dependent folding landscape of a nucleic acid." M.T. Woodside, P.C. Anthony, K. Larizadeh, W.M. Behnke-Parks, D. Herschlag, S.M. Block,
Science 314, 1001-1004 (2006).
PDF document.
"Nanomechanical measurements of the sequence-dependent folding landscapes of single nucleic acid hairpins." M.T. Woodside, W.M. Behnke-Parks, K. Larizadeh, K. Travers, D. Herschlag, S.M. Block,
Proc. Natl. Acad. Sci. USA 103, 6190-6195 (2006).
PDF document.
"Passive all-optical force clamp for high-precision laser trapping." W.J. Greenleaf, M.T. Woodside, E.A. Abbondanzieri, S.M. Block,
Phys. Rev. Lett.
95, 208102 (2005).
PDF document.
"Scanned probe imaging of single-electron charge states in nanotube quantum dots." M.T. Woodside, P.L. McEuen,
Science 296, 1098-1101 (2002).
PDF document.
"High-resolution, single-molecule measurements of biomolecular motion." W.J. Greenleaf, M.T. Woodside, S.M. Block,
Annu. Rev. Biophys. Biomol. Struct. 36, 171-190 (2007).
PDF document.
"Imaging inter edge state scattering centers in the quantum Hall regime." M.T. Woodside, C. Vale, P.L. McEuen, C. Kadow, K.D. Maranowski, A.C. Gossard,
Phys. Rev. B 64, 041310 (2001).
PDF document.
"Direct observation of hierarchical folding in single riboswitch aptamers." W.J. Greenleaf, K.L. Frieda, D.A.N. Foster, M.T. Woodside, S.M. Block,
Science 319, 630-633 (2008).
PDF document.
"Folding and unfolding single RNA molecules under tension." M.T. Woodside, C. Garcia-Garcia, S.M. Block,
Curr. Opin. Chem. Biol. 12, 640-646 (2008).
PDF document.
"Single-molecule force spectroscopy of the
add adenine riboswitch relates folding to regulatory mechanism." K. Neupane, H. Yu, D.A.N. Foster, F. Wang, M.T. Woodside,
Nucleic Acids Res 39, 7677-7687 (2011).
PDF document.
"Experimental validation of free-energy-landscape reconstruction from non-equilibrium single-molecule force spectroscopy measurements." A.N. Gupta, A. Vincent, K. Neupane, H. Yu, F. Wang, M.T. Woodside,
Nature Physics 7, 631-634 (2011). Links to
manuscript and
News & Views commentary.
"Signal-pair correlation analysis of single-molecule trajectories." A. Hoffmann, M.T. Woodside,
Angew. Chem. Int. Ed. 50, 12643-12646 (2011). Links to
manuscript and
Highlight commentary in
ChemPhysChem.
"Direct observation of multiple misfolding pathways in a single prion protein molecule." H. Yu, X. Liu, K. Neupane, A.N. Gupta, A.M. Brigley, A. Solanki, I. Sosova, M.T. Woodside,
Proc. Natl. Acad. Sci. USA 109, 5283-5288 (2012). Link to
manuscript.
"Phthalocyanine tetrasulfonates bind to mulitple sites on natively-folded prion protein." D.R. Dee, A.N. Gupta, M. Anikovskiy, I. Sosova, E. Grandi, L. Rivera, A. Vincent, A.M. Brigley, N.O. Petersen, M.T. Woodside,
BBA Proteins & Proteomics 1824, 826-832 (2012). Link to
manuscript.
"Transition path times for nucleic acid folding determined from energy-landscape analysis of single-molecule trajectories." K. Neupane, D.B. Ritchie, H. Yu, D.A.N. Foster, F. Wang, M.T. Woodside,
Phys Rev Lett 109, 068102 (2012). Links to
manuscript and
Viewpoint commentary in
Physics.
"Energy landscape analysis of native folding of the prion protein yields the diffusion constant, transition path time, and rates." H. Yu, A.N. Gupta, X. Liu, K. Neupane, A.M. Brigley, I. Sosova, M.T. Woodside,
Proc. Natl. Acad. Sci. USA 109, 14452-14457 (2012). Link to
manuscript.
"Programmed -1 frameshifting efficiency correlates with RNA pseudoknot conformational plasticity, not resistance to mechanical unfolding." D.B. Ritchie, D.A.N. Foster, M.T. Woodside,
Proc. Natl. Acad. Sci. USA 109, 16167-16172 (2012). Link to
manuscript.
2013
"Single-molecule approaches to prion protein misfolding." H. Yu, D.R. Dee, M.T. Woodside,
Prion 7, 140-146 (2013). Link to
manuscript.
2012
2011
2005 - 2010
2000 - 2005
"Single-molecule assays for investigating protein misfolding and aggregation." A. Hoffmann, K. Neupane, M.T. Woodside,
Phys Chem Chem Phys 15, 7934-7948 (2013). Link to
manuscript.