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Email: sm17@ualberta.ca Location of work: Chemical and Materials Engineering Building (Room 581) - University of Alberta Personal Details: I completed my B.S. in Chemical Engineering from Indian Institute of Technology Madras, India. I joined University of Alberta in Fall 2004 to do a PhD in Computer Process Control under the guidance of Dr.Sirish Shah. I am basically from Madras (Chennai), in southern India where I did all my schooling. I like to travel a lot and explore new places. I also enjoy playing badminton, cricket and tennis and I am a big fanatic of Tamil movies. Area of Research: "Chemometric methods for Bioinformatics: Theory and Applications of Multivariate Statistical Techniques in the analysis of NMR data" NMR spectra and mass spectra contain information on a wide range of biochemical pathways; they are both useful pathological fingerprinting tools. Chemometric methods have employed PCA in the analysis of spectra from different chemical instruments. One objective of this work is to extend these methods to the analysis of NMR spectral data. The second objective of this research project is to decipher the characteristic perturbation and shifts in these metabolic fingerprints caused by specific metabolic changes in our body, using multivariate statistical techniques. Understanding the biochemical reason for such a shift in metabolic space leads to the identification of biomarkers for different diseases. Recently I have been trying to apply Support Vector Classifiers to classify the NMR spectrums of normal people and diseased patients. The ulterior objective of this work is to figure out the combination of biomarker and also the metabolic mechanisms that causes the disease. |
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