Courses

The Department of Biochemistry currently offers twenty courses at the graduate level. Learn more about our course offerings by reading the descriptions below. If you are interested in enrolling, take note of the prerequisites and special notes for each course to ensure you are eligible. 

  • BIOCH 510 Signal Transduction

    Principles of the biochemistry of cell communication and signal transduction through receptor activation, the generation of second messengers, and the control of protein modifications. The course will emphasize the mechanisms responsible for the regulation of cell migration, division and death.

    Prerequisites:

    BIOCH 310, 320 and 330, or BIOCH 203 and 205 all with a minimum grade of B-, or consent of the Department

    Notes:

    1. Lectures are the same as for BIOCH 410, but with additional assignments and evaluation appropriate to graduate studies
    2. This course may not be taken for credit if credit has already been obtained in BIOCH 410
  • BIOCH 520 Protein Chemistry, Structure and Function

    Protein chemistry and purification. The intra- and intermolecular forces that determine protein structure. Principles of protein folding and dynamics. Enzyme mechanisms and ligand binding interactions.

    Prerequisites: 

    BIOCH 320, or BIOCH 203 and 205
    all with a minimum grade of B- or consent of Department

    Notes:

    1. Lectures are the same as for BIOCH 420, but with additional assignments and evaluation appropriate to graduate studies
    2. This course may not be taken for credit if credit has already been obtained in BIOCH 420
  • BIOCH 530 Biochemistry of Eukaryotic Gene Expression

    The organization and expression at the molecular level of information encoded in the nucleic acids of eukaryotic cells. The focus will be on genome structure and the regulation of gene expression at the levels of transcription, post-transcriptional processing, translation, post-translational modification and protein sorting. Recombinant DNA technologies and genetic engineering will be discussed as methods for studying the cellular processing of genetic information.

    Prerequisites:  

    BIOCH 320 and 330, or BIOCH 203 and 205
    all with a minimum grade of B- or consent of Department

    Notes:

    1. Lectures are the same as for BIOCH 430, but with additional assignments and evaluation appropriate to graduate studies
    2. This course may not be taken for credit if credit has already been obtained in BIOCH 430
  • BIOCH 541 Structure and Function of Biological Membranes

    Survey of the structure and function of biological membranes. Topics include the structure, properties and composition of biomembranes, characterization and structural principles of membrane lipids and proteins, lateral and transverse asymmetry, dynamics, lipid-protein interactions, membrane enzymology, permeability, and biogenesis.

    Prerequisites: 

    BIOCH 320, or BIOCH 203 and 205
    all with a minimum grade of B- or consent of Department

    Notes:

    1. Lectures are the same as for BIOCH 441, but with additional assignments and evaluation appropriate to graduate studies
    2. This course may not be taken for credit if credit has already been obtained in BIOCH 441
  • BIOCH 550 The Molecular Biology of Mammalian Viruses

    This course will focus on virus structure, replication, and interaction with host cells at the molecular level. Lytic viruses with single- or double-stranded DNA or RNA genomes will be discussed, as will the mechanisms of viral oncogenesis.

    Prerequisites:  

    BIOCH 320 and 330, or BIOCH 203 and 205
    all with a minimum grade of B- or consent of Department

    Notes:

    1. Lectures are the same as for BIOCH 450, but with additional assignments and evaluation appropriate to graduate studies
    2. This course may not be taken for credit if credit has already been obtained in BIOCH 450
  • BIOCH 555 Biochemistry of Lipids and Lipoproteins

    Advanced course focusing on specific aspects of the regulation of lipid and lipoprotein metabolism. Topics include the transcriptional and post-translational mechanisms governing the synthesis and degradation of important enzymes, lipids, and lipid transport molecules; the role of lipid mediators in signaling pathways and protein modification; the assembly and dynamics of lipoproteins and biological membranes; genetic disruptions of lipid regulatory proteins such as cell surface receptors leading to human disease.

    Prerequisites:  

    BIOCH 310, 320, and 330, or BIOCH 203 and 205
    all with a minimum grade of B- or consent of Department

    Notes:

    1. Lectures are the same as for BIOCH 455, but with additional assignments and evaluation appropriate to graduate studies
    2. This course may not be taken for credit if credit has already been obtained in BIOCH 455
  • BIOCH 565 Methods in Molecular Biophysics

    Survey of biophysical methods used in the characterization and structural determination of biological macromolecules, from ensemble measurements to single-molecule detection. Topics include mass spectrometry, optical spectroscopy, light microscopy, X-ray and neutron diffraction, electron microscopy, molecular dynamics and nuclear magnetic resonance. Emphasis is on using techniques in evaluating structure-function relationships through the discussion of representative macromolecular systems.

    Prerequisites

    BIOCH 320 with a minimum grade of B- or consent of the Department
    This course cannot be taken for credit if credit has already been obtained in BIOCH 460

    Coordinator:

    Dr. H. Young

  • BIOCH 609 Macromolecular Structure Analysis

    Principles of X-ray crystallography as applied to the study of protein and nucleic acid structure. Practical aspects of diffraction and structure solution are demonstrated by a collaborative study of a suitable small molecule of biological interest. Designed for senior honors and graduate students.

    Prerequisite:

    consent of Instructor

    Notes:

    1. Maximum enrollment of 10 students
    2. Offered in alternate years
  • BIOCH 620 Selected Topics in Protein Structure, Function and Regulation

    Directed reading and seminar course, based on papers taken from recent literature of protein research. Students critically discuss the papers and give oral presentations to the class. Designed for graduate students.

    Prerequisite:

    BIOCH 420 or equivalent, or consent of Department

  • BIOCH 623 Special Topics in Research on Polynucleotides

    This course is a journal club and discussion group in which current research topics on nucleic acids are discussed. Specific talks range from biochemistry, genetics and microbiology to nuclear biology and clinical aspects.

  • BIOCH 626 Special Topics in Protein Research

    Seminar course for advanced students. Detailed consideration is given to recent advances in research on protein structure and function and mechanism of enzyme action.

    Prerequisite

    BIOCH 420 or consent of Department

  • BIOCH 630 Selected Topics in Modern Molecular Biology

    Directed reading and seminar course, based on papers taken from the recent literature of molecular biology. Students critically discuss the papers and give oral presentations.

    Prerequisite

    BIOCH 530 and consent of the Department

    Note

    1. designed for graduate students; offered yearly
  • BIOCH 640 Special Topics in Research on Biomembranes

    Seminar course for advanced students covering selected topics from the current literature in the field of membrane structure and function.

    Prerequisite

    BIOCH 441 or consent of Department

  • BIOCH 641 Selected Topics on the Structure and Function of Biological Membranes

    Directed reading and seminar course on the structure and function of biological membranes. Topics include membrane biogenesis, bioenergetics, transport and structural aspects of membrane lipids and proteins.

    Prerequisite

    BIOCH 441 or consent of the Department

  • BIOCH 650 Signal Transduction

    A journal club and discussion group addressing topics in the general area of signalling mechanisms that control cell activation, growth, apoptosis and vesicle trafficking. Specific talks range from biochemistry, genetics and microbiology to molecular biology and clinical aspects.

    Prerequisite

    BIOCH 410/510 or consent of Department

  • BIOCH 651 Special Topics in Lipid and Lipoprotein Research

    Seminar for advanced students covering selected topics from the current literature in the field of lipid and lipoprotein research.

    Prerequisite

    BIOCH 555 or consent of Department

  • BIOCH 655 Advances in Lipid and Lipoprotein Research

    Recent developments and use of the current literature are emphasized. Topics include regulation of lipid metabolism, intracellular lipid trafficking, regulation of lipoprotein secretion, lipid transfer among lipoproteins, reverse cholesterol transport, and atherosclerosis.

    Prerequisite

    BIOCH 455, or 555, or consent of Department

    Note

    1. Offered in alternate years
  • BIOCH 670 Recent Advances in Biochemistry

    A seminar course on topics of current interest in biochemistry. Students will contribute to a presentation based on recent developments published in first rate journals. Attendance at all seminars is expected.

    Note

    Open only to graduate students in Biochemistry
  • BIOCH 671 Recent Advances in Biochemistry

    A seminar course on topics of current interest in biochemistry. Students will contribute a presentation on their research project that includes original data. Attendance at all seminars is expected. 
    Prerequisite

    BIOCH 670 or consent of the Department

    Note

    Open only to graduate students in Biochemistry
  • BIOCH 675 Magnetic Resonance in Biology and Medicine II

    Designed for advanced honors and graduate students interested in the application of nuclear magnetic resonance spectroscopy  to biological systems. Topics include quantum mechanical basis of NMR, multinuclear multidimensional NMR experiments, NMR relaxation theory, new NMR applications. 
    Prerequisite

    Consent of Instructor.

    Note

    1. Offered in alternate years.