Biochemistry

Recent Publications

 

The kidney anion exchanger 1 affects tight junction properties via claudin-4.
Lashhab R, Rumley AC, Arutyunov D, Rizvi M, You C, Dimke H, Touret N, Zimmermann R, Jung M, Chen XZ, Alexander T, Cordat E.
Sci Rep. 2019 Feb 28;9(1):3099. doi: 10.1038/s41598-019-39430-9.

Regulating the regulator: intramembrane proteolysis of vesicular trafficking proteins and the SERCA regulator phospholamban.
Young HSLemieux MJ.
EMBO Rep. 2019 Feb 25. pii: e47792. doi: 10.15252/embr.201947792. [Epub ahead of print] No abstract available.

The Phospholamban Pentamer Alters Function of the Sarcoplasmic Reticulum Calcium Pump SERCA.
Glaves JP, Primeau JO, Espinoza-Fonseca LM, Lemieux MJYoung HS.
Biophys J. 2019 Feb 19;116(4):633-647. doi: 10.1016/j.bpj.2019.01.013. Epub 2019 Jan 22.

Quantitative Multiplex Substrate Profiling of Peptidases by Mass Spectrometry.
Lapek JD Jr, Jiang Z, Wozniak JM, Arutyunova E, Wang SC, Lemieux MJ, Gonzalez DJ, O'Donoghue AJ.
Mol Cell Proteomics. 2019 Jan 31. pii: mcp.TIR118.001099. doi: 10.1074/mcp.TIR118.001099.[Epub ahead of print]

Isoniazid induces a monocytic-like phenotype in HL-60 cells.
Babu D, Khan SR, Srivastava N, Kyoung Suh LY, Morgan AG, Aljuhani N, Fahlman RP, Siraki AG.
Arch Biochem Biophys. 2019 Jan 22. pii: S0003-9861(17)30842-1. doi: 10.1016/j.abb.2019.01.004. [Epub ahead of print]

Formylation of Eukaryotic Cytoplasmic Proteins: Linking Stress to Degradation.
Eldeeb MA, Fahlman RP, Esmaili M, Fon EA.
Trends Biochem Sci. 2019 Jan 17. pii: S0968-0004(18)30274-3. doi: 10.1016/j.tibs.2018.12.008. [Epub ahead of print]

The Prion 2018 round tables (I): The structure of PrPSc.
Baskakov IV, Caughey B, Requena JR, Sevillano AM, Surewicz WK, Wille H.
Prion. 2019 Jan 15. doi: 10.1080/19336896.2019.1569450. [Epub ahead of print]

Non-canonical BAD activity regulates breast cancer cell and tumor growth via 14-3-3 binding and mitochondrial metabolism.
Mann J, Githaka JM, Buckland TW, Yang N, Montpetit R, Patel N, Li L, Baksh S, Godbout R, Lemieux H, Goping IS.
Oncogene. 2019 Jan 11. doi: 10.1038/s41388-018-0673-6. [Epub ahead of print]

A role for phosphatidylcholine and phosphatidylethanolamine in hepatic insulin signaling.
van der Veen JN, Lingrell S, McCloskey N, LeBlond ND, Galleguillos D, Zhao YY, Curtis JM, Sipione S, Fullerton MD, Vance DE, Jacobs RL.
FASEB J. 2019 Jan 7:fj201802117R. doi: 10.1096/fj.201802117R. [Epub ahead of print]

Vitamin E alleviates non-alcoholic fatty liver disease in phosphatidylethanolamine N-methyltransferase deficient mice.
Presa N, Clugston RD, Lingrell S, Kelly SE, Merrill AH Jr, Jana S, Kassiri Z, Gómez-Muñoz A, Vance DE, Jacobs RL, van der Veen JN.
Biochim Biophys Acta Mol Basis Dis. 2019 Jan;1865(1):14-25. doi: 10.1016/j.bbadis.2018.10.010. Epub 2018 Oct 6.

Understanding Conformational Dynamics of Complex Lipid Mixtures Relevant to Biology.
Friedman R, Khalid S, Aponte-Santamaría C, Arutyunova E, Becker M, Boyd KJ, Christensen M, Coimbra JTS, Concilio S, Daday C, van Eerden FJ, Fernandes PA, Gräter F, Hakobyan D, Heuer A, Karathanou K, Keller F, Lemieux MJ, Marrink SJ, May ER, Mazumdar A, Naftalin R, Pickholz M, Piotto S, Pohl P, Quinn P, Ramos MJ, Schiøtt B, Sengupta D, Sessa L, Vanni S, Zeppelin T, Zoni V, Bondar AN, Domene C.
J Membr Biol. 2018 Dec;251(5-6):609-631. doi: 10.1007/s00232-018-0050-y. Epub 2018 Oct 22. Review.

Lipin 2/3 phosphatidic acid phosphatases maintain phospholipid homeostasis to regulate chylomicron synthesis.
Zhang P, Csaki LS, Ronquillo E, Baufeld LJ, Lin JY, Gutierrez A, Dwyer JR, Brindley DN, Fong LG, Tontonoz P, Young SG, Reue K.
J Clin Invest. 2018 Dec 3. pii: 122595. doi: 10.1172/JCI122595. [Epub ahead of print]