Recent Publications


Structural polymorphisms in fibrillar aggregates associated with exfoliation syndrome.
Ghaffari Sharaf M, Amidian S, Rathod V, Crichton A, Damji KF, Wille H, Unsworth LD.
Sci Rep. 2020 Sep 28;10(1):15860. doi: 10.1038/s41598-020-72737-6.

TSPAN1 promotes autophagy flux and mediates cooperation between WNT-CTNNB1 signaling and autophagy via the MIR454-FAM83A-TSPAN1 axis in pancreatic cancer.
Zhou C, Liang Y, Zhou L, Yan Y, Liu N, Zhang R, Huang Y, Wang M, Tang Y, Ali DW, Wang Y, Michalak M, Chen XZ, Tang J.
Autophagy. 2020 Sep 25. doi: 10.1080/15548627.2020.1826689. Online ahead of print.

Cytokine trafficking of IL-9 and IL-13 through TfnRc+ vesicles in activated human eosinophils.
Almas S, Fayad N, Srivastava O, Siddique M, Touret N, Lacy P.J
Leukoc Biol. 2020 Sep 10. doi: 10.1002/JLB.2MA0820-320RR. Online ahead of print.

Lipid Phosphate Phosphatases and Cancer.
Tang X, Brindley DN.
Biomolecules. 2020 Sep 2;10(9):E1263. doi: 10.3390/biom10091263. Review.

Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication.
Vuong W, Khan MB, Fischer C, Arutyunova E, Lamer T, Shields J, Saffran HA, McKay RT, van Belkum MJ, Joyce MA, Young HS, Tyrrell DL, Vederas JC, Lemieux MJ.
Nat Commun. 2020 Aug 27;11(1):4282. doi: 10.1038/s41467-020-18096-2.

Structure and function of proteins in membranes and nanodiscs.
Lemieux MJ, Overduin M.
Biochim Biophys Acta Biomembr. 2020 Aug 22;1863(1):183445. doi: 10.1016/j.bbamem.2020.183445. Online ahead of print.

Autoinhibition of TRPV6 Channel and Regulation by PIP2.
Cai R, Liu X, Zhang R, Hofmann L, Zheng W, Amin MR, Wang L, Hu Q, Peng JB, Michalak M, Flockerzi V, Ali DW, Chen XZ, Tang J.
iScience. 2020 Aug 8;23(9):101444. doi: 10.1016/j.isci.2020.101444. Online ahead of print.

Role of Adipose Tissue-Derived Autotaxin, Lysophosphatidate Signaling, and Inflammation in the Progression and Treatment of Breast Cancer.
Brindley DN, Tang X, Meng G, Benesch MGK.
Int J Mol Sci. 2020 Aug 18;21(16):5938. doi: 10.3390/ijms21165938. Review.

Selective enhancement of cardiomyocyte efficiency results in a pernicious heart condition.
Groenendyk J, Wang Q, Wagg C, Lee D, Robinson A, Barr A, Light PE, Lopaschuk GD, Agellon LB, Michalak M.
PLoS One. 2020 Aug 13;15(8):e0236457. doi: 10.1371/journal.pone.0236457. eCollection 2020.

Molecular Mechanisms of Fuchs and Congenital Hereditary Endothelial Corneal Dystrophies.
Malhotra D, Casey JR.
Rev Physiol Biochem Pharmacol. 2020 Aug 14. doi: 10.1007/112_2020_39. Online ahead of print.

Homogeneous nanodiscs of native membranes formed by stilbene-maleic-acid copolymers.
Esmaili M, Brown CJ, Shaykhutdinov R, Acevedo-Morantes C, Wang YL,Wille H, Gandour RD, Turner SR, Overduin M.
Nanoscale. 2020 Aug 20;12(32):16705-16709. doi: 10.1039/d0nr03435e.

Role of pH Regulatory Proteins and Dysregulation of pH in Prostate Cancer.
Fliegel L.
Rev Physiol Biochem Pharmacol. 2020 Aug 11. doi: 10.1007/112_2020_18. Online ahead of print.

LncRNA PVT1 promotes gemcitabine resistance of pancreatic cancer via activating Wnt/β-catenin and autophagy pathway through modulating the miR-619-5p/Pygo2 and miR-619-5p/ATG14 axes.
Zhou C, Yi C, Yi Y, Qin W, Yan Y, Dong X, Zhang X, Huang Y, Zhang R, Wei J, Ali DW, Michalak M, Chen XZ, Tang J.Mol
Cancer. 2020 Jul 29;19(1):118. doi: 10.1186/s12943-020-01237-y.

Vitamin D is an endogenous partial agonist of the transient receptor potential vanilloid 1 channel.
Long W, Fatehi M, Soni S, Panigrahi R, Philippaert K, Yu Y, Kelly R, Boonen B, Barr A, Golec D, Campbell SA, Ondrusova K, Hubert M, Baldwin T, Lemieux MJ, Light PE.
J Physiol. 2020 Jul 28. doi: 10.1113/JP279961. Online ahead of print.

Molecular mechanism of intermediate filament recognition by plakin proteins.
Mohammed F, Trieber C, Overduin M, Chidgey M.
Biochim Biophys Acta Mol Cell Res. 2020 Jul 23;1867(11):118801. doi: 10.1016/j.bbamcr.2020.118801. Online ahead of print.PMID: 32712070 Review.

Uev1A amino terminus stimulates poly-ubiquitin chain assembly and is required for NF-κB activation.
Wu Z, Andersen PL, Moraes T, McKenna SA, Zhang Y, Zhang W, Ellison MJ, Xiao W.
Cell Signal. 2020 Jul 11;74:109712. doi: 10.1016/j.cellsig.2020.109712. Online ahead of print.

Human red blood cell uptake and sequestration of arsenite and selenite: Evidence of seleno-bis(S-glutathionyl) arsinium ion formation in human cells.
Kaur G, Javed W, Ponomarenko O, Shekh K, Swanlund DP, Zhou JR, Summers KL, Casini A, Wenzel MN, Casey JR, Cordat E, Pickering IJ, George GN, Leslie EM.
Biochem Pharmacol. 2020 Jul 8;180:114141. doi: 10.1016/j.bcp.2020.114141. Online ahead of print.