The following courses are available to graduate students:
BIOCH 510 Signal Transduction
Principles of the biochemistry of cell communication and signal transduction through receptor activation, the generation of second messengers, and the control of protein modifications. The course will emphasize the mechanisms responsible for the regulation of cell migration, division and death. Prerequisites: BIOCH 310, 320 and 330, or BIOCH 203 and 205, all with a minimum grade of B-, or consent of the Department. Lectures are the same as for BIOCH 410, but with additional assignments and evaluation appropriate to graduate studies. This course may not be taken for credit if credit has already been obtained in BIOCH 410.
BIOCH 650 Signal Transduction Journal Club
A journal club and discussion group addressing topics in the general area of signalling mechanisms that control cell activation, growth, apoptosis and vesicle trafficking. Specific talks range from biochemistry, genetics and microbiology to molecular biology and clinical aspects. Prerequisite: BIOCH 410/510 or consent of Department.
CELL 502 The Birth and Death of a Cell
An advanced course dealing with cell differentiation, intracellular and extracellular signaling processes, the cell cycle, apoptosis and necrosis. Consists of lecture material and small group learning sessions. Topics include stem cell research, cancer therapy and human disorders involving cell death (e.g. Alzheimer’s and cardiovascular disease). Will require reading and discussion of current research articles. Lectures are the same as for CELL 402 but with additional assignments and evaluation appropriate to graduate studies. May not be taken if credit has already been obtained in CELL 402. Prerequisites: Consent of the Department.
ONCOL 520 - Tumor Biology
The course will provide an introduction to the basic science of oncology. Topics to be covered comprise: the genetic basis of cancer, including the role of proto-oncogenes and tumor suppressor genes; mechanisms of carcinogenesis and radiation-sensitivity, including DNA repair and cell cycle control; the molecular basis of tumor metastasis, including cell motility, tumor cell invasion, and extravasation; tumor immunology and angiogenesis; cancer genetics, and epigenetics; experimental therapies; stem cells; cancer imaging; metabolism and palliation. Course offered in alternate (even-numbered) years. Prerequisites: BIOCH 200, and one of the following: BIOCH 320 or 330 or ONCOL 320.
ONCOL 524 - Nutrition and Metabolism Related to Cancer
A lecture and reading course to address nutritional issues specifically related to cancer prevention, diagnosis, treatment and recovery. Lectures are the same as for ONCOL 424, but with additional assignments and evaluation appropriate to graduate studies. Credit will only be given for one of ONCOL 524, 424 and AFNS 524, 424. Prerequisite: (NUTR 301 and 302) or (NUFS 352 and 6Œ Biochemistry) or ONCOL 320.
ONCOL 570 - Directed Reading in Experimental Oncology
Reading and discussion of current research literature on selected topics in experimental oncology under the direction of one or more faculty members. Topics presently available include cell adhesion mechanisms, cell cycle regulation, DNA repair, radiotherapy and susceptibility and resistance, oncogenes/tumor suppressor genes, and tumor cell metastasis. Notes: (1) Grades will be based on participation in group discussions and/or written reports from assigned readings with emphasis on critical evaluation of the subject matter. (2) Students in other graduate programs may register with the consent of Instructors. Prerequisite: consent of Department.
ONCOL 580 - Molecular Imaging: Tracers, Targets, Techniques
This course will provide an overview of molecular imaging probes and their application in basic and clinical science. The course will have an emphasis on radionuclide based probes and on their application in oncology but will also introduce other classes of probes (optical, MR, x-ray contrast, ultrasound and photoacoustic) and other pathologies. The course will examine imaging techniques, cell and tissue targets for imaging probes, the chemical elaboration of molecular imaging probes and some applications in the diagnosis and treatment of human disease. Molecular imaging in drug development will also be addressed. Prerequisite: Consent of the Department.
ONCOL 620 - Recent Advances in Cancer Research
A directed reading and seminar course based on recent developments in the cellular and molecular biology of cancer. The students will critically review papers selected from the recent literature and give oral presentations. Prerequisites: ONCOL 520 and consent of Department. Offered in alternate years.
ONCOL 660 - Current Topics in Cancer Research
A general seminar/discussion course on recent advances in a wide range of topics related to cancer development and management. Selected topics include experimental therapeutics, molecular oncogenetics, tumour immunobiology, DNA repair, and cell cycle regulation. Notes: (1) all graduate students in the Department of Oncology are expected to attend the seminars whether or not they are registered in the course. (2) All graduate students in the Department of Oncology should register in the course in their second year and present a seminar based on their research project. (3) All graduate students registered in ONCOL 660 will write a paper on a selected topic. Restricted to graduate students in the Department of Oncology.
ONCOL 661 - Current Topics in Cancer Research II
A general seminar course based on recent advances in a wide range of topics related to cancer. Note: Oncology 661 should be taken in the first term of the year in which Oncology 660 is taken. Graduate students must obtain one credit from ONCOL 661 in order to meet the minimum requirements for the MSc and PhD programs in the Department of Oncology. Restricted to graduate students in the Department of Oncology