Current Research
Project Name |
Investigator |
Funding Agencies |
Theme |
| A Multicentre Concealed‐Allocation Parallel‐Group Blinded Randomized Controlled Trial to Ascertain the Effect of High‐Dose Intravenous Vitamin C Compared to Placebo on Mortality or Persistent Organ Dysfunction at 28 Days in Septic Intensive Care Unit Patients (LOVIT) | Dr. J Kutsogiannis | Infectious Disease | |
| A Multi-centre, Adaptive, Randomized, Open-label, Controlled Clinical Trial of the Safety and Efficacy of Investigational Therapeutics for the Treatment of COVID-19 in Hospitalized Patients (CATCO) |
Dr. J Kutsogiannis |
Infectious Disease | |
| A Multi-centre, Adaptive, Randomized, open-label, Controlled Clinical Trial of the Safety and Efficacy of Investigational Therapeutics for the Treatment of COVID-19 in Hospitalized Patients (CATCO) In Conjunction with the Public Health Emergency Solidarity Trial. | Dr. C O’Neil Dr. E MacIntyre |
Infectious Disease | |
| Aneurysmal Subarachnoid Hemorrhage - Red Blood Cell Transfusion and Outcome (SAHaRA) | Dr. J Kutsogiannis | Neurosciences | |
| Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness: A Randomized Controlled Trial (BALANCE) | Dr. W Sligl | Sunnybrook Research Institute | Infectious Disease |
| Best Practices In Prolonged Mechanical Ventilation: A Qualitative Examination of Patient, Family and Healthcare Provider Perspectives. | Dr. E MacIntyre | Respiratory Science | |
| Canadian Severe Acute Infection Outbreak and Pandemic Preparedness Study: Short Period Incidence Study of Severe Acute Respiratory Infection (Sprint-Sari) | Dr. J Kutsogiannis Dr. O Rewa |
Infectious Disease | |
| Continuous Renal Replacement Therapy Protocol: CRRTnet A Multicenter Data Registry for Outcomes for Continuous Renal Replacement Therapy | Dr. S Bagshaw Dr. O Rewa |
CC Nephrology | |
| Dissected Aorta Repair Through Stent Implantation (DARTS): Registry | Dr. M Moon | CC Cardiology | |
| Frailty, Outcomes, Recovery and Care Steps of Critically Ill Patients (FORECAST) | Dr. O Rewa | Frailty | |
| HEMOglobin transfusion threshold in Traumatic brain Injury OptimizatioN: The HEMOTION TRIAL PROTOCOL | Dr. J Kutsogiannis | Neurosciences | |
| Immune Response & Immune Function | Dr. W Sligl | Infectious Disease | |
| Lessening Organ Dysfunction with Vitamin C (LOVITT) | Dr. O Rewa | Perioperative Medicine | |
| Lessening Organ Dysfunction with VITamin C; A Multicentre Concealed-Allocation Parallel-Group Blinded Randomized Controlled Trial to Ascertain the Effect of High-Dose Intravenous Vitamin C Compared to Placebo on Mortality or Persistent Organ Dysfunction at 28 Days in Hospitalized Patients with COVID-19 (Lovit-Covid) | Dr. J Kutsogiannis | Infectious Disease | |
| Myocardial Ischemia and Transfusion (MINT) | Dr. J Senaratne | CC Cardiology | |
| Neurological Complications of COVID 19 | Dr. J Kutsogiannis | Infectious Disease | |
| Nimodipine Pharmacokinetic Variability and its Impact on Outcomes in Patients with Aneurysmal Subarachnoid Hemorrhage: A Prospective Observational Study (Nimodipine) | Dr. J Kutsogiannis | Neurosciences | |
| Prolonged Mechanical Ventilation: A 10 year provincial Retrospective Cohort Study. | Dr. E Macintyre | Respiratory Science | |
| PROphylaxis for Venous ThromboEmbolism in Severe Traumatic Brain Injury, a double-blind Randomized Controlled Trial (PROTEST) | Dr. J Kutsogiannis Dr. Mahmoud |
CIHR | Neurosciences |
| Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community Acquired Pneumonia (REMAP-CAP) | Dr. J Kutsogiannis Dr. W Sligl |
RAH Foundation | Infectious Disease |
| Relaxation for Critically ill Patient Outcomes and Stress Coping Enhancement (REPOSE): Pilot Clinical trial of an integrative intervention to improve adult critically ill patients’ delirium and related outcomes. | E Papathanassoglou K Scherr |
Perioperative Medicine | |
| REVISE | Dr. O Rewa | Perioperative Medicine | |
| Sedation, Analgesia and Delirium MANagement: an international audit of adult medical, surgical, trauma, and neuro-intensive care patients | Dr. J Kutsogiannis | Neurosciences | |
| Short Period Incidence Study of Severe Acute Respiratory Infection (SPRINT-SARI) | Dr. O Rewa | RAH Foundation | Infectious Disease |
| The ExtraCorporeal Membrane Oxygenation for 2019 novel Coronavirus Acute Respiratory Disease (ECMO-CARD) | Dr. G Singh | Infectious Disease | |
| The Frequency of Screening and SBT Technique Trial: The FAST Trial A North American Weaning Collaboration (FAST) | Dr. J Kutsogiannis | Respiratory Science | |
| The measurement of Cough Peak Flows to predict liberation from mechanical ventilation or tracheostomy in respiratory and neurological subgroups of critically ill patients (CPF) | Dr. J Kutsogiannis | Respiratory Science | |
| The New Edmonton Cervical Spine Board: (NECs Board) Trial | Dr. J Kutsogiannis | Neurosciences | |
| The Use of Capnographic Late Dead Space Fraction and Clinical Prediction Rules in the Prediction of Pulmonary Embolism in Critically Ill Patients Undergoing Computed Tomography of the Chest or Ventilation Perfusion Scanning (Deadspace) | Dr. J Kutsogiannis | Respiratory Science |