Department of Critical Care

Peer Reviewed Grants


  • Dr Constantine Dean Karvellas

    Agency

    Project Title

    Role

    University of Alberta Hospital Foundation Standard versus Accelerated Initiation of Renal Replacement Therapy in Acute Kidney Injury (STARRT-AKI) Co-I
    Transplant Fund Value Added Ophthalmic acid as an oxidative biomarker in patients with acute liver failure PI
    Transplant Fund Value Added Validation of pre-operative scoring systems and renal biomarkers in critically ill patients with acute on chronic liver failure assessed for liver transplantation PI
    Schering-Plough/Merck Canada at arms length Grant Renal biomarkers in critically ill patients with acute on chronic liver failure assessed for liver transplantation PI
  • Dr Jim Kutsogiannis

    Agency

    Project Title

    Role

    Canadian Institutes for Health Research (CIHR) Thromboprophylaxis After Significant Traumatic Brain Injury: A Randomized Controlled Trial Co-I
    Ontario Neurotrauma Foundation Thromboprophylaxis After Significant Traumatic Brain Injury: A Randomized Controlled Trial Co-I
    Canadian Institutes of Health Research (CIHR) Project Scheme Relaxation for critically ill Patient Outcomes and Stress- coping Enhancement (REPOSE): Clinical Trial of an Integrative Intervention to improve critically ill patients' delirium and related outcomes Co-I
    Canadian Institutes of Health Research (CIHR) Project Scheme Probiotics to prevent Severe Pneumonia and Endotracheal Colonization Trial Co-I
    Canadian Institutes for Health Research (CIHR) Advance Care Planning Evaluation in Elderly Patients: A multi-center, prospective study (The ACCEPT Study) Co-I
    Canadian Intensive Care Foundation A Randomized Trial of Supplemental Parenteral Nutrition in Under and over Weight Critically Ill Patients:  The TOP UP Trial Co-PI
    Canadian Institutes for Health Research (CIHR) Acute Heart Failure – Emergency Management Co-I
    Royal Alexandra Hospital Foundation Royal Alexandra Critical Care Research Co-I
    Rick Hansen Foundation Man in Motion Rick Hansen Spinal Cord Injury Registry Co-I
    Physician’s Services Incorporated Foundation Determination of Death after Cardiac Arrest Co-I
    Children’s Hospital of Eastern Ontario Research Institute Pilot Study for the Determination of Death after Cardiac Arrest PI
    Royal Alexandra Hospital Foundation & Royal Alexandra Hospital Nursing Research Fund Effects of An ICU Diary on Post Traumatic Stress Disorder Symptoms in Intensive Care Unit (ICU) Survivors and Family Members  Co-I
    Value-Added Grants Committee Alveolar Recruitment Manoeuvers in Lung Donors PI
    Canadian Institutes for Health Research (CIHR) Realities, Expectations and Attitudes to LIfe Support Technologies in Intensive Care for Octogenarians (The REALISTIC 80 Study) Co-I
    Canadian Institutes for Health Research (CIHR) Daily sedative interruption in ICU patients being managed with a sedation protocol Co-I
    Canadian Institutes for Health Research/ Fresenius Kabi A Randomized Trial of Glutamine and Antioxidant Supplementation in Critically Ill Patients Co-I
    Johnson & Johnson Inc. Quality of Life after Video Assisted Thoracoscopic Surgery (VATS) Anatomical Lung Resection for Lung Cancer Co-I
  • Dr Rachel Khadaroo

    Agency

    Project Title

    Role

    American College of Surgeons (ACS) James Carrico Faculty Research Fellowship for the Study of Trauma and Critical Care The Role of Oncostatin M in Organ Injury following Acute Intestinal Ischemia/Reperfusion PI
    Surgical Infection Society (SIS) Junior Faculty Fellowship The Role of Oncostatin M (OSM) in Sepsis and Multiple Organ Dysfunction  PI
    University of Alberta Hospital Foundation The molecular mechanism of intestinal derived factor-induced acute lung injury PI
    University of Alberta Hospital Foundation Improved multi-organ dysfunction by targeting oncostatin M/Oncostatin M Receptor Co-I
    University of Alberta Hospital Foundation A potential therapy for intestinal ischemic-reperfusion injury Co-I
    Edmonton Civic Employees Charitable Assistance Fund Intestinal derived factors role in acute lung injury PI
    Women and Children’s Health Research Institute Innovation Grant Use of vasopressin in the resuscitation of neonates with hypoxia-reoxygenation injury: a randomized blinded controlled trial in the swine model of neonate hypoxia-reoxygenation Co-I
    Centre for Excellence for Gastrointestinal Inflammation and Immunity Research The role of bacterial translocation in the development of acute lung injury PI
    Centre for Excellence for Gastrointestinal Inflammation and Immunity Research

    Metabolomic profiling to characterize acute intestinal ischemia/reperfusion injury

    PI
  • Dr Sean M Bagshaw

    Agency

    Project Title

    Role

    Partnership for Research and Innovation in the Health System
    Identifying and Evaluating Intensive Care Unit Capacity Strain in Alberta
    PI
    Partnership for Research and Innovation in the Health System
    Reassessing Practices in the Daily Care of Critically Ill Patients: Building Capacity and Methodology to Identify & Close Evidence-care Gaps
    Co-PI
    The University Hospital Foundation
    COMParison of Angiotensin Converting enzyme inhibitor management strategies prior to coronary artery bypass surgery (the COMPACT trial): a pilot randomized controlled registry study
    Co-I
    Canadian Institutes for Health Research
    Emerging research and clinical priorities in the detection and management of frailty in older patients across acute care settings
    Co-Appl
    Technology Evaluation in the Elderly Network
    OPTIMAL Selection for and Timing to Start Renal Replacement in Critically Ill Older Patients with Acute Kidney Injury (OPTIMAL-AKI)
    PI
    MSI Foundation
    A Prospective Multi-centre Observational Study of Frailty in Cardiac Surgery in Alberta
    PI
    The University Hospital Foundation
    Intra-Operative Continuous Renal Replacement Therapy in Liver Transplantation: A phase II randomized controlled trial
    PI
    The University Hospital Foundation
    Does Enteral Glutamine Improve Outcomes in Cardiovascular Surgical Patients? A Phase II Randomized, Blinded, Placebo-Controlled Trial
    Co-PI
    Academic Health Science Centre AFP Innovation Fund
    Point Prevalence Study of Barriers to Acute Rehabilitation in Canadian Intensive Care Units
    Co-I
    Canadian Institutes of Health Research Early Determination of long-term Prognosis in critically ill patients with Severe Traumatic Brain Injury (TBI-Prognosis multicenter prospective study) Co-I
    Physician Services Incorporated Health Research Grant Optimizing Duration of Antibiotic Therapy for Bloodstream Infections: a multi-centre retrospective study Co-I
    Canadian Institutes for Health Research Transfusion Requirements in Cardiac Surgery II (TRICS II) Co-I
    Canadian Institutes for Health Research Standard versus Accelerated Initiation of Renal Replacement Therapy in Acute Kidney Injury (STARRT-AKI) Co-PI
    Canadian Institutes for Health Research A prospective multicentre observational study of frailty in critically illness (ICU FRAILTY Study) PI
    The University Hospital Foundation Standard versus Accelerated Initiation of Renal Replacement Therapy in Acute Kidney Injury (STARRT-AKI) PI
    The University Hospital Foundation A prospective multicentre observational study of frailty in critically illness (ICU FRAILTY Study) PI
    The Canadian Intensive Care Foundation A prospective multicentre observational study of frailty in critically illness (ICU FRAILTY Study) PI
  • Dr Wendy Sligl

    Agency

    Project Title

    Role

    University of Alberta Hospital Foundation Premorbid Functional Status Predicts Mortality in Critically Ill Patients with Community-Acquired Pneumonia PI