Department of Critical Care

Recent Publications

Academic Faculty Publications

  • Constantine Karvellas

    Peer-Reviewed

    Cardoso FS, Gottfried M, Tujios S, Olson JC, Karvellas CJ; US Acute Liver Failure Study Group. Continuous renal replacement therapy is associated with reduced serum ammonia levels and mortality in acute liver failure. Hepatology. 2018 Feb 67(2):711-720
    Kok B, Karvellas CJ, Abraldes JG, Jalan R, Sundaram V, Gurka D, Keenan S, Kumar A, Martinka G, Bookatz B, Wood G, Kumar A; Cooperative Antimicrobial Therapy of Septic Shock (CATSS) Research Group. The impact of obesity in cirrhotic patients with septic shock: a retrospective cohort study. Liver Int. 2018 Jul;38(7):1230-1241
    Kok B, Lester ELW, Lee WM, Hanje AJ, Stravitz RT, Girgis S, Patel V, Peck JR, Esber C, Karvellas CJ; United States Acute Liver Failure Study Group. Acute Liver Failure from Tumor Necrosis Factor-α Antagonists: Report of Four Cases and Literature Review. Dig Dis Sci. 2018 Jun;63(6):1654-1666. 
    Sundaram V, Jalan R, Ahn JC, Charlton MR, Goldberg DS, Karvellas CJ, Noureddin M, Wong R. Class III (morbid) obesity is an independent risk factor for acute on chronic liver failure in patients with decompensated cirrhosis. J Hepatol. 2018 Sep;69(3):617-625
    Bajaj JS, Moreau R, Kamath PS, Vargas HE, Arroyo V, Reddy KR, Szabo G, Tandon P, Olson J, Karvellas CJ, Tustot T, Lai J, Wong F. Acute-on-Chronic Liver Failure: Getting ready for prime-time? Hepatology. 2018 Apr 24. [Epub ahead of print]IF 13.2
    Speiser JL, Wolff, BJ, Chung D, Karvellas CJ, Koch DG, Durkalski VL. BiMM tree: A decision tree method for modeling clustered and longitudinal binary outcomes. Commun Stat Simul Comput. 2018 Sept 12. (Epub ahead of print).
    Geib T, LeBlanc A, Shiao TC, Roy R, Leslie EM, Karvellas CJ, Sleno L. Absolute quantitation of acetaminophen-modified human serum albumin in acute liver failure patients by LC-MS/MS Rapid Communications in Mass Spectrometry. Rapid Commun Mass Spectrom. 2018 Jun 19. doi: 10.1002/rcm.8206. [Epub ahead of print]
    Karvellas CJ, Garcia-Lopez E, Fernandez J, Saliba F, Sy E, Jalan R, Pavesi M, Gustot T, Ronco JJ, Arroyo V; Chronic Liver Failure Consortium and European Foundation for the Study of Chronic Liver Failure. Dynamic Prognostication in Critically Ill Cirrhotic Patients with Multiorgan Failure in ICUs in Europe and North America: A Multicenter Analysis. Crit Care Med. 2018 Nov;46(11):1783-1791.
    Speiser JL, Karvellas CJ, Shumilak G, Sligl WI,  Mirzanejad Y, Gurka D, Kumar A, Kumar A. Predicting In-Hospital Mortality in Pneumonia-Associated Septic Shock Patients Using a Classification and Regression Tree: A Nested Cohort Study. Journal of Intensive Care (in press) 2018.
    Karvellas CJ, Dong V, Abraldes JG, Lester ELW, Kumar A. The impact of delayed source control and antimicrobial therapy in 196 patients with cholecystitis-associated septic shock: a cohort analysis. Can J Surg 2018 (in press)

    Peer-Reviewed: Invited Reviews

    Parker A, Karvellas CJ. Coagulation Defects in the Cirrhotic Patient Undergoing Liver Transplantation. Transplantation. 2018 Sep;102(9):1453-1458. 
    Cardoso FS, Karvellas CJ. Respiratory Complications Before and After Liver Transplant. J Intensive Care Med. 2018 Jan. [Epub ahead of print]
    Kok B, Dong V, Karvellas CJ. Graft dysfunction and management in liver transplantation. Crit Care Clin 2018 (in press). 
    MacDonald AM, Karvellas CJ. Current evidence for the emerging role of extracorporeal support in acute and acute-on-chronic liver failure. Semin Respir Crit Care Med. 2018 (in press)
  • David Zygun

    Peer-Reviewed

    Rewa OG, Stelfox HT, Ingolfsson A, Zygun DA, Featherstone R, Opgenorth D, Bagshaw SM. Indicators of intensive care unit capacity strain: a systematic review.Crit Care. 2018 Mar 27;22(1):86. 
    Bagshaw SM, Wang X, Zygun DA, Zuege D, Dodek P, Garland A, Scales DC, Berthiaume L, Faris P, Chen G, Opgenorth D, Stelfox HT. Association between strained capacity and mortality among patients admitted to intensive care: A path-analysis modeling strategy. J Crit Care. 2018 Feb;43:81-87
     Hall A, Stelfox H, Wang X, Chen G, Zuege D, Dodek P, Garland A, Scales D,  Berthiaume L, Zygun D, Bagshaw S. Association between after hours admission to the intensive care unit, strained capacity,  and mortality: a retrospective cohort study. Critical Care. 2018 April  22:97
     Brundin-Mather R, Soo A, Zuege DJ, Niven DJ, Fiest K, Doig CJ, Zygun D, Boyd JM, Parsons Leigh J, Bagshaw SM, Stelfox HT. Secondary EMR data for quality improvement and research: A comparison of manual and electronic data collection from an integrated critical care electronic medical record system. Journal of Critical Care 47 (2018) 295-301 
     Opgenorth D, Stelfox HT, Gilfoyle E, Gibney RTN, Meier M, Boucher P, McKinlay D, McIntosh C, Wang W, Zygun DA, Bagshaw SM. Perspectives on strained intensive care unit capacity: A survey of critical care professionals. PLoS ONE 13(8): e0201524
     van Diepen S, Tran DT, Ezekowitz JA, Zygun DA, Katz JN, Lopes RD, Newby LK, McAlisterFA, Kaul P. The high cost of critical care unit over-utilization for patients with NSTE ACS.  American Heart Journal Volume 202, August 2018, Pages 84-88.
     Sauro KM, Soo A, Kramer A, Couillard P, Kromm J,  Zygun D, Niven DJ, Bagshaw SM, Stelfox HT. Venous thromboembolism prophylaxis in neurocritical care patients: Are current practices, best practices? Neurocritical Care2018 Oct 1. [Epub ahead of print]
  • Jim Kutsogiannis

    Peer-Reviewed

    Alberda C, Marcushamer S, Hewer T, Journault N, Kutsogiannis D. Feasibility of a Lactobacillus casei Drink in the Intensive Care Unit for Prevention of Antibiotic Associated Diarrhea and Clostridium difficile. Nutrients. 2018 Apr 26;10(5).
    White CW, Messer SJ, Large SR, Conway J, Kim DH, Kutsogiannis DJ, Nagendran J, Freed DH. Transplantation of Hearts Donated after Circulatory Death. Front Cardiovasc Med. 2018 Feb 13;5:8. 
    Rolfes MA, Gross FL, Flannery B, Meyers AFA, Luo M, Bastien N, Fowler RA, Katz JM, Levine MZ, Kumar A, Uyeki TM; CSIS and ROSII Study Groups . Kinetics of Serological Responses in Critically Ill Patients Hospitalized With 2009 Pandemic Influenza A(H1N1) Virus Infection in Canada, 2009-2011. J Infect Dis. 2018 Mar 13;217(7):1078-1088.

    Published Abstracts/Poster Presentations

    NOTE: **denotes international meeting | *denotes national meeting

    Doucette K, Worton K, Kutsogiannis DJ and Preiksaitis J. Utilization of Increased Risk Donors in a Canadian Multi-Organ Transplant Program. Joint Conference with American Society of Transplant Surgeons and American Society of Transplantation, Philadelphia (USA), May 2015. **
    Le Roux P, Suarez J. PRINCE: Point Prevalence Study In Neurocritical Care. Point Prevalance Cross Sectional Observational, Non-Interventional Study. Annual Neurocritical Care Conference in Seattle, WA (USA), September 2014. **
    Zytaruk Z, Duffett M, Lauzier F,Ye C, Dodek PM, Paunovic B, Fowler R, Kho ME, Foster D,Stelfox T, Sinuff T, Clarke F, Wood G,Cox M, Kutsiogiannis DJ, Jacka M,Roussos M, Kumar K, Guyatt G and Cook DJ, for the CONECCKT-T. Investigators and the Canadian Critical Care Trials Group. Barriers and Facilitators of Thromboprophylaxis for Medical-Surgical ICU Patients: A Multicenter Survey . Am J Resp Crit Care Med 2014 (Abstract).
    Centofanti J, Zytaruk N, Foster D, Martinka G, Hand L, Karachi T, Mehta S, Granton J, Muscedere J, O’Callaghan N, Dodek P, Ashley BJ, McIntyre LL, Watpool I,Kutsiogiannis DJ, Jacka M, Fowler R, Wood G, Auld F, Cook DJ for the CONECCKTT Investigators and the CCCTG. Pre-printed Orders for Thromboprophylaxis in the ICU: A Cross-Sectional Analysis. American Thoracic Society Meeting, San Diego, California, May 16-21, 2014.**
  • Michael Jacka
    Beattie WS, Wijeysundera DN, Chan MTV, Peyton PJ, Leslie K, Paech MJ, Sessler DI, Wallace S, Myles PS, Galagher W, Farrington C, Ditoro A, Baulch S, Sidiropoulos S, Bulach R, Bryant D, O'Loughlin E, Mitteregger V, Bolsin S, Osborne C, McRae R, Backstrom M, Cotter R, March S, Silbert B, Said S, Halliwell R, Cope J, Fahlbusch D, Crump D, Thompson G, Jefferies A, Reeves M, Buckley N, Tidy T, Schricker T, Lattermann R, Iannuzzi D, Carroll J, Jacka M, Bryden C, Badner N, Tsang MWY, Cheng BCP, Fong ACM, Chu LCY, Koo EGY, Mohd N, Ming LE, Campbell D, McAllister D, Walker S, Olliff S, Kennedy R, Eldawlatly A, Alzahrani T, Chua N, Sneyd R, McMillan H, Parkinson I, Brennan A, Balaji P, Nightingale J, Kunst G, Dickinson M, Subramaniam B, Banner-Godspeed V, Liu J, Kurz A, Hesler B, Fu AY, Egan C, Fiffick AN, Hutcherson MT, Turan A, Naylor A, Obal D, Cooke E; ANZCA Clinical Trials Network for the ENIGMA-II Investigators. Implication of Major Adverse Postoperative Events and Myocardial Injury on Disability and Survival: A Planned Subanalysis of the ENIGMA-II Trial. Anesth Analg. 2018 Mar 12
    Jacka MJ, Guyatt G, Mizera R, Van Vlymen J, Ponce de Leon D, Schricker T, Bahari MY, Lv B, Afzal L, Plou García MP, Wu X, Nigro Maia L, Arrieta M, Rao-Melacini P, Devereaux PJ. Age Does Not Affect Metoprolol's Effect on Perioperative Outcomes (From the POISE Database). Anesth Analg. 2018 Apr;126(4):1150-1157
    Buse GL, Manns B, Lamy A, Guyatt G, Polanczyk CA, Chan MTV, Wang CY, Villar JC, Sigamani A, Sessler DI, Berwanger O, Biccard BM, Pearse R, Urrútia G, Szczeklik W, Garutti I, Srinathan S, Malaga G, Abraham V, Chow CK, Jacka MJ, Tiboni M, Ackland G, Macneil D, Sapsford R, Leuwer M, Le Manach Y, Devereaux PJ. Troponin T monitoring to detect myocardial injury after noncardiac surgery: a cost-consequence analysis. Can J Surg. 2018 Jun;61(3):185-194. 
  • Sean Bagshaw
      Bagshaw SM, Wald R. Indications and Timing of Continuous Renal Replacement Therapy Application. Contrib Nephrol. 2018;194:25-37
      Rewa OG, Stelfox HT, Ingolfsson A, Zygun DA, Featherstone R, Opgenorth D, Bagshaw SM. Indicators of intensive care unit capacity strain: a systematic review.Crit Care. 2018 Mar 27;22(1):86.
      Shears M, Takaoka A, Rochwerg B, Bagshaw SM, Johnstone J, Holding A, Tharmalingam S, Millen T, Clarke F, Rockwood K, Li G, Thabane L, Muscedere J, Stelfox HT, Cook DJ; Canadian Critical Care Trials Group. Assessing frailty in the intensive care unit: A reliability and validity study. J Crit Care. 2018 Feb 8;45:197-203
      Klein SJ, Brandtner AK, Lehner GF, Ulmer H, Bagshaw SM, Wiedermann CJ, Joannidis M. Biomarkers for prediction of renal replacement therapy in acute kidney injury: a systematic review and meta-analysis. Intensive Care Med. 2018 Mar;44(3):323-336
      Fernando SM, Reardon PM, Bagshaw SM, Scales DC, Murphy K, Shen J, Tanuseputro P, Heyland DK, Kyeremanteng K. Impact of nighttime Rapid Response Team activation on outcomes of hospitalized patients with acute deterioration. Crit Care. 2018 Mar 14;22(1):67.
      Shaw AD, Bagshaw SM. Fluid Therapy in the Critically Ill. Crit Care Clin. 2018 Apr;34(2):xiii-xiv.
      Douvris A, Malhi G, Hiremath S, McIntyre L, Silver SA, Bagshaw SM, Wald R, Ronco C, Sikora L, Weber C, Clark EG. Interventions to prevent hemodynamic instability during renal replacement therapy in critically ill patients: a systematic review. Crit Care. 2018 Feb 22;22(1):41
      Daneman N, Rishu AH, Pinto R, Aslanian P, Bagshaw SM, Carignan A, Charbonney E, Coburn B, Cook DJ, Detsky ME, Dodek P, Hall R, Kumar A, Lamontagne F, Lauzier F, Marshall JC, Martin CM, McIntyre L, Muscedere J, Reynolds S, Sligl W, Stelfox HT, Wilcox ME, Fowler RA; Canadian Critical Care Trials Group. 7 versus 14 days of antibiotic treatment for critically ill patients with bloodstream infection: a pilot randomized clinical trial. Trials. 2018 Feb 17;19(1):111
      Sutherland SM, Goldstein SL, Bagshaw SM. Acute Kidney Injury and Big Data. Contrib Nephrol. 2018;193:55-67
      Brown KN, Leigh JP, Kamran H, Bagshaw SM, Fowler RA, Dodek PM, Turgeon AF, Forster AJ, Lamontagne F, Soo A, Stelfox HT. Transfers from intensive care unit to hospital ward: a multicentre textual analysis of physician progress notes. Crit Care. 2018 Jan 28;22(1):19
       Alobaidi R, Morgan C, Basu RK, Stenson E, Featherstone R, Majumdar SR, Bagshaw SM. Association Between Fluid Balance and Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. JAMA Pediatr. 2018 Mar 1;172(3):257-268.
       Garg AX, Shehata N, McGuinness S, Whitlock R, Fergusson D, Wald R, Parikh C, Bagshaw SM, Khanykin B, Gregory A, Syed S, Hare GMT, Cuerden MS, Thorpe KE, Hall J, Verma S, Roshanov PS, Sontrop JM, Mazer CD. Risk of Acute Kidney Injury in Patients Randomized to a Restrictive Versus Liberal Approach to Red Blood Cell Transfusion in Cardiac Surgery: A Substudy Protocol of the Transfusion Requirements in Cardiac Surgery III Noninferiority Trial. Can J Kidney Health Dis. 2018 Jan 3;5:2054358117749532
       Shehata N, Whitlock R, Fergusson DA, Thorpe KE, MacAdams C, Grocott HP, Rubens F, Fremes S, Lellouche F, Bagshaw SM, Royse A, Rosseel PM, Hare G, Medicis E, Hudson C, Belley-Cote E, Bainbridge D, Kent B, Shaw A, Byrne K, Syed S, Royse CF, McGuiness S, Hall J, Mazer CD. Transfusion Requirements in Cardiac Surgery III (TRICS III): Study Design of a Randomized Controlled Trial. J Cardiothorac Vasc Anesth. 2018 Feb;32(1):121-129. 
       Fujii T, Ganeko R, Kataoka Y, Furukawa TA, Featherstone R, Doi K, Vincent JL, Pasero D, Robert R, Ronco C, Bagshaw SM. Polymyxin B-immobilized hemoperfusion and mortality in critically ill adult patients with sepsis/septic shock: a systematic review with meta-analysis and trial sequential analysis. Intensive Care Med. 2018 Feb;44(2):167-178
       Ostermann M, McCullough PA, Forni LG, Bagshaw SM, Joannidis M, Shi J, Kashani K, Honore PM, Chawla LS, Kellum JA; all SAPPHIRE Investigators. Kinetics of Urinary Cell Cycle Arrest Markers for Acute Kidney Injury Following Exposure to Potential Renal Insults. Crit Care Med. 2018 Mar;46(3):375-383
       Bagshaw SM, Wang X, Zygun DA, Zuege D, Dodek P, Garland A, Scales DC, Berthiaume L, Faris P, Chen G, Opgenorth D, Stelfox HT. Association between strained capacity and mortality among patients admitted to intensive care: A path-analysis modeling strategy. J Crit Care. 2018 Feb;43:81-87. 
       Hall A, Stelfox H, Wang X, Chen G, Zuege D, Dodek P, Garland A, Scales D,  Berthiaume L, Zygun D, Bagshaw S. Association between after hours admission to the intensive care unit, strained capacity,  and mortality: a retrospective cohort study. Critical Care. 2018 April  22:97
       Bove T, Belletti A, Putzu A, Pappacena S, Denaro G, Landoni G, Bagshaw SM, Zangrillo A. Intermittent furosemide administration in patients with or at risk for acute kidney injury: Meta-analysis of randomized trials. PLoS One. 2018 Apr 24;13(4):e0196088.
       Au SS, Roze des Ordons AL, Parsons Leigh J, Soo A, Guienguere S, Bagshaw SM, Stelfox HT. A Multicenter Observational Study of Family Participation in ICU Rounds. Crit Care Med. 2018 May 7.
       de Grood C, Parsons Leigh J, Bagshaw S, Dodek P, Fowler R, Forster A, Boyd J, Stelfox T. Patient, family and provider experiences with transfers from intensive care unit to hospital ward: a multicentre qualitative study. CMAJ June 04, 2018 190 (22) E669-E676
       Rewa O, Eurich D, Gibney N, Bagshaw S. A modified Delphi process to identify, rank and prioritize quality indicators for continuous renal replacement therapy (CRRT) care in critically ill patients. Journal of Critical Care 47 (2018) 145–152 
       Brundin-Mather R, Soo A, Zuege DJ, Niven DJ, Fiest K, Doig CJ, Zygun D, Boyd JM, Parsons Leigh J, Bagshaw SM, Stelfox HT. Secondary EMR data for quality improvement and research: A comparison of manual and electronic data collection from an integrated critical care electronic medical record system. Journal of Critical Care 47 (2018) 295-301 
       Stelfox HT, Soo A, Niven DJ, Fiest KM, Wunsch H, Rowan KM, Bagshaw SM. Assessment of the Safety of Discharging Select Patients Directly Home From the Intensive Care Unit. A Multicenter Population-Based Cohort Study. JAMA Intern Med. Published online August 20, 2018 
       Opgenorth D, Stelfox HT, Gilfoyle E, Gibney RTN, Meier M, Boucher P, McKinlay D, McIntosh C, Wang W, Zygun DA, Bagshaw SM. Perspectives on strained intensive care unit capacity: A survey of critical care professionals. PLoS ONE 13(8): e0201524
       Hoste EJ, Kellum,  JA, Selby NM, Zarbock A, Palevsky PM, Bagshaw SM, Goldstein SL, Cerdá J, Chawla LS. Global epidemiology and outcomes of acute kidney injury. Nature Reviews Nephrology 22 August 2018 
       Mazer CD, Whitlock RP, Fergusson DA, Belley-Cote E, Connolly K, Khanykin B, Gregory AJ, de Médicis É, Carrier FM, McGuinness S, Young PJ, Byrne K, Villar JC, Royse A, Grocott HP, Seeberger MD, Mehta C, Lellouche F, Hare GMT, Painter TW, Fremes S, Syed S, Bagshaw SM, Hwang NC, Royse C, Hall J, Dai D, Mistry N, Thorpe K, Verma S, Jüni P, Shehata N; TRICS Investigators and Perioperative Anesthesia Clinical Trials Group.  Six-Month Outcomes after Restrictive or Liberal Transfusion for Cardiac Surgery. N Engl J Med. 2018 Aug 
       Young PJ, Bagshaw SM, Forbes A, Nichol A, Wright SE, Bellomo R, Bailey MJ4, Beasley RW, Eastwood GM, Festa M, Gattas D, van Haren F, Litton E, Mouncey PR, Navarra L, Pilcher D, Mackle DM, McArthur CJ, McGuinness SP, Saxena MK, Webb S, Rowan KM; Australian and New Zealand Intensive Care Society Clinical Trials Group on behalf of the PEPTIC investigators A cluster randomised, crossover, registry-embedded clinical trial of proton pump inhibitors versus histamine-2 receptor blockers for ulcer prophylaxis therapy in the intensive care unit (PEPTIC study): study protocol. Crit Care Resusc. 2018 Sep;20(3):182-189.
       Montgomery C, Rolfson DB, Bagshaw SM. Frailty and the Association Between Long-Term Recovery After Intensive Care Unit Admission. Crit Care Clin - (2018) In Press.
       Rolfson DB, Heckman GA, Bagshaw SM, Robertson D, Hirdes JP, On Behalf Of Canadian Frailty Network. Implementing Frailty Measures in The Canadian Healthcare System. J Frailty Aging 2018;in press; Published on line.
       Sauro KM, Soo A, Kramer A, Couillard P, Kromm J,  Zygun D, Niven DJ, Bagshaw SM, Stelfox HT. Venous thromboembolism prophylaxis in neurocritical care patients: Are current practices, best practices? Neurocritical Care2018 Oct 1. 
       Dellinger RP, Bagshaw SM, Antonelli A, Foster DM, Klein DJ, Marshall JC, Palevsky PM, Weisberg LS, Shorr CA,  Trzedak S, Walker PM. Effect of Targeted Polymyxin B Hemoperfusion on 28-Day Mortality in Patients With Septic Shock and Elevated Endotoxin Level: The EUPHRATES Randomized Clinical Trial. JAMA. 2018;320(14):1455-1463. 
       Rolfson DB, Heckman GA, Bagshaw SM, Robertson D, Hirdes JP, Canadian Frailty Network. Implementing Frailty Measures in the Canadian Healthcare System. J Frailty Aging (2018) 7: 208.
  • Sean van Diepen
    van Diepen S, Tran DT, Ezekowitz JA, Zygun DA, Katz JN, Lopes RD, Newby LK, McAlister FA, Kaul P. The High Cost of Critical Care Unit Over-Utilization for Patients with NSTE ACS. American Heart Journal 2018; 202, 84-88:
    Mebazaa A, Combes A, van Diepen S, Hollinger A, Katz JN, Landoni G, Hajjar LA, Lassus J, Lebreton G, Montalescot G, Park JJ, Price S, Sionis A, Yannopolos D, Harjola VP; Levy B, Thiele H. Management of Cardiogenic Shock Complicating Myocardial Infarction. Intensive Care Medicine 2018
    McAlister FA, Youngson E, van Diepen S, Ezekowitz JA, Kaul P. Influence of hospital volume on outcomes for patients with heart failure: Evidence from a Canadian national cohort study. American Heart Journal 2018
    Sun LY, Chung AM, Farkouh ME, van Diepen S, Weinberger J, Bourke M, Ruel M. Defining an Intraoperative Hypotension Threshold in Association with Stroke in Cardiac Surgery. Anesthesiology 2018
    Purdy G, James M, Wakefield P, Skow R, van Diepen S, May L, Davenport M, Steinback C. Maternal cardioautonomic responses during and following exercise throughout pregnancy. Applied Physiology, Nutrition, and Metabolism 2018
    Verma S, Kaul P, Lin M, Ezekowitz JA, Zygun D, McAlister FA, van Diepen S. Acute coronary syndromes and heart failure CCU utilization and outcomes in teaching and community hospitals: A national population based analysis. Canadian Journal of Cardiology 2018
    Alviar CL, Miller E, McAreavey D, Soble J, Moriyama B, Lee B, van Diepen S, Soble M, Morrow DA. A Guide to Positive Pressure Ventilation in the Cardiac Intensive Care Unit: Clinical Perspective from the ACC Critical Care Cardiology Working Group. Journal of the American College of Cardiology 2018
    Tsui AKY, Lyon ME, van Diepen S, Goudreau BL, Thomas D, Higgins T, Raizman JE, Füzéry AK, Rodriguez-Capote K, Estey M, Cembrowski G. Selection of optimal cutoff for diverse point-of-care and central laboratory troponin I assays. The Journal of Applied Laboratory Medicine 2018

    Abstract

    Senaratne J, Norris C, McClure R, Nagendran J, Butler C, Meyer S, Anderson T, van Diepen S. Adherence to cardiac surgical waitlist guidelines is a poor predictor of cardiac surgery waitlist mortality. European Heart Journal 2017; 38(1S):A2200.
    Anselm D, Peng M, van Diepen S, Schnell G. Observed versus predicted mortality in patients with acute coronary syndromes and low-risk grace scores. Canadian Journal of Cardiology 2017; 33 (10S): 170
    Miller R, van Diepen S, Schnell G, Grant A. Comparative prognostic accuracy of cardiogenic shock risk prediction models. Canadian Journal of Cardiology 2017; 33 (10S): 319
    van Diepen S, Tran DT, Ezekowitz JA, Zygun DA, Katz JN, Lopes RD, Newby LK, McAlister FA, Kaul P. The high cost of low acuity non ST-segment elevation acute coronary syndrome admissions to the coronary care unit: an analysis of national population health data. Journal of the American College of Cardiology. 2017; 69 (Supplement 11) : 287
  • Wendy Sligl
    Daneman N, Rishu AH, Pinto R, Aslanian P, Bagshaw SM, Carignan A, Charbonney E, Coburn B, Cook DJ, Detsky ME, Dodek P, Hall R, Kumar A, Lamontagne F, Lauzier F, Marshall JC, Martin CM, McIntyre L, Muscedere J, Reynolds S, Sligl W, Stelfox HT, Wilcox ME, Fowler RA; Canadian Critical Care Trials Group. 7 versus 14 days of antibiotic treatment for critically ill patients with bloodstream infection: a pilot randomized clinical trial. Trials. 2018 Feb 17;19(1):111
    Shumilak G, Sligl W. Moving Past the Routine Use of Macrolides—Reviewing the Role of Combination Therapy in Community-Acquired Pneumonia. Respiratory Infections First Online: 06 September 2018 

Clinical Faculty Publications

  • 2018

    Peer-Reviewed

    Macala K, Khadaroo RG, Panahi S, Gragasin FS, Bourque SL.  Low dose intralipid resuscitation improves survival compared to ClinOleic in propranolol overdose in rats.   PLoS One. 2018 Aug 30;13(8) e-collection.
    Saravana-Bawan B, Warkentin LM, Rucker D, Carr F, Churchill TA, Khadaroo RG.  Incidence and Predictors of Post-operative Delirium in the Elderly Acute Care Surgery Population: A Prospective Study.  Canadian Journal of Surgery (Accepted April 2018).
    Mueller K, Kokotilo MS, Carter J, Thiesen A, Madsen KL, Studzinski J, Khadaroo RG, Churchill TA.  Creatine-loading preserves intestinal barrier function during organ preservation.  Cryobiology.  (Published online 01 Aug 2018) doi: 10.1016/j.cryobiol.2018.07.009.
    Eamer GJ, Al-Amoodi M, Holroyd-Leduc JM, Rolfson DB, Warkentin LM, Khadaroo RG. Review of Risk Assessment Tools to Predict Morbidity and Mortality in Elderly Surgical Patients.  The American Journal of Surgery (Published online 18 April 2018).
    McComb A, Warkentin LM, McNeely M, Khadaroo RG. Development of a Reconditioning Program for Elderly Abdominal Surgery Patients: the Elder-friendly Approaches to the Surgical Environment - BEdside reconditioning for Functional ImprovemenTs (EASE-BE FIT) Pilot Study.  World Journal of Emergency Surgery 2018-May-21; 13:21 (E-collection).
    Pilieci S, Salim SY, Heffernan DS, Itani K, Khadaroo RG.  A Randomized Controlled Trial of Video Education versus Skill Demonstration: Which is More Effective in Teaching Sterile Surgical Technique?  Surgical Infections (Larchmt). 2018 Apr;19(3):303-312.
    Li Y, Pederson JL, Churchill TA, Wagg AS, Holroyd-Leduc JM, Alagiakrishnan K, Padwal RS, Khadaroo RG.  Impact of frailty on outcomes after discharge in older surgical patients: a prospective cohort study.  CMAJ. 2018 Feb 20;190(7):E184-E190
    Eamer GJ, Clement F, Pederson JL, Church TA, Khadaroo RG. Analysis of Post-Discharge Costs Following Emergent General Surgery in the Elderly.  Canadian Journal of Surgery. 2018 Feb;61(1):19-27
    Eamer GJ, Taheri A, Chen SS, Daviduck Q, Chambers T, Shi X, Khadaroo RG.  Comprehensive geriatric assessment for older people admitted to a surgical service.  Cochrane Database Syst Rev. 2018 Jan 31.