Royal Alexandra Hospital Critical Care Research and Quality Assurance Group
Royal Alexandra Hospital Critical Care Research and Quality Assurance Group
Site Lead Investigator: Dr. J Kutsogiannis
Research Contacts: Pat Thompson & Tayne Hewer
Office: 780-735-4096
About the site:
The General Systems Unit at the Royal Alexandra Hospital is a 30-bed adult intensive care unit located in an inner city teaching hospital. The clinical research group has a rich history of nearly 30 years, actively participating in academic investigator-initiated, CIHR, and industry-funded clinical trials and cohort studies.
Our research focuses on specialized areas such as sepsis, renal replacement therapy, substance use disorder, respiratory failure, pneumonia and ARDS as it relates to mechanical ventilation, enteral and parenteral nutrition, end of life care and family satisfaction with care, as well as providing support to other researchers within the Royal Alexandra Hospital, including trauma, spine, and thoracic surgery.
| Theme | Current Project | Invesitgator |
| Infectious Disease | A Multicentre Concealed‐Allocation Parallel‐Group Blinded Randomized Controlled Trial to Ascertain the Effect of High‐Dose Intravenous Vitamin C Compared to Placebo on Mortality or Persistent Organ Dysfunction at 28 Days in Septic Intensive Care Unit Patients (LOVIT) | Dr. J Kutsogiannis |
| Neurosciences | HEMOglobin transfusion threshold in Traumatic brain Injury OptimizatioN: The HEMOTION TRIAL PROTOCOL | Dr. J Kutsogiannis |
| Neurosciences | Aneurysmal Subarachnoid Hemorrhage - Red Blood Cell Transfusion and Outcome (SAHaRA) | Dr. J Kutsogiannis |
| Respiratory Science | The measurement of Cough Peak Flows to predict liberation from mechanical ventilation or tracheostomy in respiratory and neurological subgroups of critically ill patients (CPF) | Dr. J Kutsogiannis |
| Respiratory Science | The Use of Capnographic Late Dead Space Fraction and Clinical Prediction Rules in the Prediction of Pulmonary Embolism in Critically Ill Patients Undergoing Computed Tomography of the Chest or Ventilation Perfusion Scanning (Deadspace) | Dr. J Kutsogiannis |
| Respiratory Science | The Frequency of Screening and SBT Technique Trial: The FAST Trial A North American Weaning Collaboration (FAST) | Dr. J Kutsogiannis |
| Neurosciences | The New Edmonton Cervical Spine Board: (NECs Board) Trial |
Dr. Fox |
| Neurosciences | Nimodipine Pharmacokinetic Variability and its Impact on Outcomes in Patients with Aneurysmal Subarachnoid Hemorrhage: A Prospective Observational Study (Nimodipine) |
Dr. Mahmoud |
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PROphylaxis for Venous ThromboEmbolism in Severe Traumatic Brain Injury, a double-blind Randomized Controlled Trial (PROTEST) | Dr. J Kutsogiannis |
| Neurosciences | Sedation, Analgesia and Delirium MANagement: an international audit of adult medical, surgical, trauma, and neuro-intensive care patients | Dr. J Kutsogiannis |
| Infectious Disease | Randomized, Embedded, Multifactorial Adaptive Platform trial for Community-Acquired Pneumonia (REMAP-CAP) | Dr. J Kutsogiannis |
| Covid-19 Studies | ||
| Infectious Disease | Neurological Complications of COVID 19 | Dr. J Kutsogiannis |
| Infectious Disease | Canadian Severe Acute Infection Outbreak and Pandemic Preparedness Study: Short Period Incidence Study of Severe Acute Respiratory Infection (Sprint-Sari) |
Dr. O Rewa |
| Infectious Disease | A Multi-centre, Adaptive, Randomized, Open-label, Controlled Clinical Trial of the Safety and Efficacy of Investigational Therapeutics for the Treatment of COVID-19 in Hospitalized Patients (CATCO) |
Dr. G Singh |
| Infectious Disease | Lessening Organ Dysfunction with VITamin C; A Multicentre Concealed-Allocation Parallel-Group Blinded Randomized Controlled Trial to Ascertain the Effect of High-Dose Intravenous Vitamin C Compared to Placebo on Mortality or Persistent Organ Dysfunction at 28 Days in Hospitalized Patients with COVID-19 (Lovit-Covid) | Dr. J Kutsogiannis |