Julianne Gibbs-Davis

Associate Professor, Faculty of Science - Chemistry

Contact

Associate Professor, Faculty of Science - Chemistry
Email
gibbsdav@ualberta.ca
Phone
(780) 492-7140
Address
E3-52A Chemistry Centre - East
11227 Saskatchewan Drive NW
Edmonton AB
T6G 2G2

Overview

About

BA Arizona State University
PhD Northwestern University


Research

Molecular Recognition at Buried Solid/Liquid Interfaces

Many systems, from the cellular environment to biosensors and heterogeneous catalysis, involve noncovalent interactions between species in solution and those confined to a membrane or solid. Directly monitoring such binding events is difficult because few techniques are sensitive to interactions at an interface and are instead overwhelmed by the sea of molecules in the bulk. However, using surface specific nonlinear optical techniques such as second harmonic generation (SHG) and sum frequency generation (SFG), we can selectively observe interfacial binding allowing us to characterize the thermodynamic and kinetic parameters governing these processes without the use of bulky labels, in situ and in real time.


 

 

Courses

CHEM 351 - Introduction to Chemical Biology

Introduction to chemical strategies used to analyze and manipulate biochemical systems. Topics may include chemical synthesis of biopolymers, protein-small molecule interactions, chemoenzymatic synthesis, enzyme-inhibitor kinetics, assay design, characterization of bioorganic samples, and various chemical biology methods. Prerequisites: CHEM 263 and BIOCH 200.


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