Laboratory Medicine and Pathology

Neuropathology, Education & Research

Clinical Services

Neurosurgical specimens

  • Diagnosis of primary and metastatic brain/spinal cord/skull base tumours, as well as non-neoplastic lesions (e.g. CNS vasculitis, encephalitis, vascular malformations) requiring neuropathological diagnosis.
  • Highly integrated molecular neuropathology.

Muscle and nerve biopsies

  • ~100-125 muscle biopsies are received annually for pathological diagnosis of neuromuscular disorders.
  • Categories of diseases encountered include (but are not limited to): inflammatory myopathies and neuropathies, neurogenic myopathy, muscular dystrophies, and demyelinating neuropathies. 

Neuro-autopsy

  • Post-mortem examination remains the gold standard for diagnosis of many neurological diseases (e.g. Alzheimer’s Disease, Multiple sclerosis, etc…) and highlights the preponderance of co-morbidities and clinically unsuspected diagnoses.
  • Post-mortem examination is an important quality assurance tool that can be used to improve the quality of patient care, assess treatment efficacy and examine treatment mechanisms.
  • Tissue can be donated for research and/or brain banking to encourage development of innovative treatments and diagnostic markers for rare and devastating neurological diseases. Please contact the Neuropathology Specialty Group for further details.

Forms and Protocols


Education

We offer Neuropathology Clinical Rotations for:

  • Postgraduate trainees:
    • Residents from Adult Neurology, Pediatric Neurology, Neurosurgery, Anatomical/General Pathology.
    • Elective resident/fellow rotations (by request).
  • Undergraduate medical students: UAlberta medical students, visiting medical students.

UAlberta Courses: MLSCI250, LABMP400/500, LABMP593 and Neurology block (UGME).


Research

Current areas of active research include:

  • Multiple sclerosis & white matter disease.
  • Epilepsy.
  • Neurodegenerative diseases.
  • Brain tumours – molecular signatures of primary & metastatic brain tumours.
  • Infectious neurological diseases.
  • Vascular disease/stroke.

Refer to individual faculty pages for further information/updates regarding these research projects.