Matthias Götte, MSc, PhD

Portrait of Matthias Gotte

Professor and Chair, Department of Medical Microbiology & Immunology

Li Ka Shing Institute of Virology, University of Alberta


Office Location: 6-020 Katz Group Centre for Pharmacy and Health Research
Office Phone: (780) 492-2309

Research Interests


Research in Dr. Götte's laboratory is focused on the study of viral replication, its inhibition and mechanisms associated with drug resistance. His interests cover a broad range of important human pathogens including RNA viruses with a high epidemic potential.

In 1997, Dr. Götte obtained his Ph.D. degree at the Max-Planck-Institute for Biochemistry in Martinsried, Germany. He started his independent research in 2000 following a three-year period of postdoctoral training at the Lady Davis Institute for Medical Research in Montreal. Dr. Götte later joined the Department of Microbiology & Immunology at McGill University and was promoted to Full Professor in 2011. Results from his laboratory have contributed to the development of novel classes of viral polymerase inhibitors. His team elucidated the mechanism of action of the investigational drug remdesivir that is now used in several countries to treat COVID-19 patients with severe disease. Dr. Götte has published approximately 130 peer-reviewed papers in the field of virology and antivirals. His research program is funded through national and provincial grants, and contracts from industry.

Research Publications