Dr. Winship is an Associate Professor and a former Alberta Innovates Health Solutions Scholar (2010-2017) in the Department of Psychiatry at the University of Alberta. As Director of the Neurochemical Research Unit (NRU), he works with a diverse group of scientists that are investigating the fundamental neurobiology of the CNS and performing clinical translational research to develop new therapies for psychiatric and neurological disorders.
PMCOL 412 (stroke, epilepsy, and pharmacotherapy)
PSYCH 511 (models of psychiatric disorders)
ResearchResearch in the Winship lab combines advanced imaging and behavioural neuroscience to better understand how the integrated CNS functions and identify key pathophysiological or adaptive processes in brain disease. These insights are used to develop new therapies for disorders including stroke, multiple sclerosis, and schizophrenia. Key areas of current research include the pathophysiology of schizophrenia (CIHR, in collaboration with John Howland, USask), collateral blood flow and collateral therapeutics during stroke (HSFC; QNRF, in collaboration with Ashfaq Shuaib), and plasticity after stroke as a target for therapy (CIHR, in collaboration with Karim Fouad).
animal models, blood flow imaging, chondroitin sulfate proteoglycans, collateral blood flow, collateral therapeutics, extracellular matrix; rehabilitation, functional neuroanatomy, maternal immune activation, schizophrenia; extracellular matrix; animal models, stroke, stroke; spinal cord; plasticity; recovery, two photon microscopy
Technologists: Yonglie Ma and Tricia Kent
Graduate Students: Mischa Bandet, Wes Paylor, Eszter Wendlandt, Junqiang Ma, Somnath Gupta, Sima Abbasi Hibashi, Celestina Tanase
Administrative assistance: Trudy Valliere
Selected Recent Publications
Ma J, Ma Y, Shuaib A, Winship IR. Impaired Collateral Flow in Pial Arterioles of Aged Rats During Ischemic Stroke. Transl Stroke Res. 2019 Jun 15. doi: 10.1007/s12975-019-00710-1. [Epub ahead of print] PubMed PMID: 31203565.
Paylor JW, Wendlandt E, Freeman TS, Greba Q, Marks WN, Howland JG, Winship IR. Impaired Cognitive Function after Perineuronal Net Degradation in the Medial Prefrontal Cortex. eNeuro. 2018 Dec 28;5(6). pii: ENEURO.0253-18.2018. PubMed PMID: 30627657; PubMed Central PMCID: PMC6325561.
Wiersma AM, Fouad K, Winship IR. Enhancing Spinal Plasticity Amplifies the Benefits of Rehabilitative Training and Improves Recovery from Stroke. J Neurosci. 2017 Nov 8;37(45):10983-10997. PubMed PMID: 29025926; PubMed Central PMCID: PMC6596489.
Ma J, Ma Y, Dong B, Bandet MV, Shuaib A, Winship IR. Prevention of the collapse of pial collaterals by remote ischemic perconditioning during acute ischemic stroke. J Cereb Blood Flow Metab. 2017 Aug;37(8):3001-3014. . PubMed PMID: 27909265; PubMed Central PMCID: PMC5536804.
Paylor JW, Lins BR, Greba Q, Moen N, de Moraes RS, Howland JG, Winship IR. Developmental disruption of perineuronal nets in the medial prefrontal cortexafter maternal immune activation. Sci Rep. 2016 Nov 23;6:37580. PubMed PMID: 27876866; PubMed Central PMCID: PMC5120325.
Director, Neurochemical Research Unit
Chair, Education Committee for Campus Alberta Neuroscience
Member, Steering Committee for the Neuroscience and Mental Health Institute
Member, Steering Committee for Campus Alberta Neuroscience.
Doctor of Philosophy
- University of Alberta
Bachelor of Science
- University of Alberta