Genes and development, obesity, psychiatric disorders; mouse models for Prader-Willi syndrome; molecular basis of human genetic disorders.
Research in the Wevrick laboratory focuses on genetic disorders that affect human development. We have specific interests in pediatric obesity, developmental delay, and also study developmental aspects of gene regulation. We identified genes that are inactivated in Prader-Willi syndrome, a sporadic chromosomal disorder that causes neonatal hypotonia, developmental delay, compulsive overeating leading to obesity, and abnormalities of sleep and respiration. We are currently studying the roles of these genes in the normal development of the nervous, muscular, and endocrine systems. Two genes, necdin and MAGEL2, have specific roles in growth and differentiation. We are using mouse models to evaluate the normal roles of these proteins and the effect of their loss in Prader-Willi syndrome.
If you are interested in a graduate student or postdoctoral position in my laboratory, please contact me at firstname.lastname@example.org, and include your cv.
Sources of Funding:
Projects in the Wevrick laboratory are funded by the Canadian Institutes of Health Research, the Natural Sciences and Engineering Research Council, the Foundation for Prader-Willi Research, the Simons Foundation for Autism Research and the Women and Children's Health Research Institute. We also gratefully acknowledge funding from the Prader-Willi Syndrome Association of Alberta, the Foundation for Prader-Willi Research (Canada) and One SMALL Step.
Donations in support of Prader-Willi Syndrome research in the Wevrick laboratory can be made by contacting the Office of Advancement at 1-888-799-9899, emailing email@example.com, or by visiting "www.giving.ualberta.ca/ContactUs.aspx"
Doctor of Philosophy
- University Of Toronto
Honors Bachelor of Sciences
- Queen's University