Faculty Members

Xin-Min Li

Professor and Chair
Department of Psychiatry
    Contact details are for academic matters only.

About Me

I am a Professor and Chair of the Department of Psychiatry in the Faculty of Medicine and Dentistry at the University of Alberta. Prior to joining the University of Alberta in 2013, I was the Director of the International Medical Graduate Program and a clinician researcher for the Institute of Advanced Medicine at the University of Manitoba. I obtained my MD and PhD in Physiology from Norman Bethune University in Changchun, China.


Research

As a clinician scientist in the field of biological psychiatry and neuropharmacology, I have been a leader in the advancement of the theory of white matter dysfunction and neurodegeneration in psychiatric disorders.

My laboratory approaches mental health disorders as neurodegenerative disorders. We examine whether central white matter damage can produce the behavioural symptoms and brain pathology in experimental animal models of schizophrenia or depression.

We examine whether antipsychotics and antidepressant treatment can prevent white matter damage and/or facilitate recovery which suggests a new role for these treatments and also suggests a new target for future drug development.

A new research direction for the lab involves the study of neurostimulation as a potential treatment for depression. We use a mouse model of depression to examine the effects of treatment with ultrasound or repetitive transcranial magnetic stimulation (rTMS) on both the brain and behaviour.  

Research Keywords

mental health, depression, schizophrenia, white matter, neurostimulation