My career goal is to develop and grow a respected thrombosis program at the University of Alberta. To this end, I have cross-disciplinary collaborations at the local and national level and have focused my research, educational, clinical and administrative commitments to this important area in medicine.
Dr. Cynthia Wu is recognized in Edmonton for her expertise in venous thromboembolism (VTE). Dr. Wu’s medical school and internal medical residency training was completed at the University of Alberta and followed by a hematology residency at McMaster University in Hamilton. She was a clinical scholar and fellow in thrombosis at the Juravinski Center in Hamilton, returning to Alberta in 2010 to join the Division of Hematology.
Leadership and Collaborations:
Dr. Wu is a thrombosis expert for consulting physicians. She created and is director of the Cancer Associated Thrombosis (CAT) Clinic located in the Kaye Edmonton Clinic. As of 2019, the CAT Clinic has had more than 4000 patient visits. Dr. Wu is also director of the new thrombosis elective rotation for medical trainees. She is a local principal investigator for various thrombosis clinical trials and heads thrombosis clinical trials within the Hematology Division. She is the Alberta lead for the Quality of Care and Effectiveness Research platform of the Canadian Venous Thromboembolism Clinical Trials and Outcomes Research (Can VECTOR) Network.
Dr. Wu has won several awards during her training and academic career including a University of Alberta Hospital Champions of Care award, the Michael Mant award and Honourable Mention for the Teacher of the Year Award for Sub-specialties.
Dr. Wu is involved in all levels of medical education, specializing in the field of VTE. She has created a Thrombosis rotation for trainees mainly targeted at internal medicine and hematology fellows. She provides clinical and research supervision to residents and fellows and informally mentors other trainees with an interest in hematology and thrombosis. Dr. Wu actively delivers many trainee educational sessions including academic half-day lectures, in-rotation small group sessions and grand rounds for multiple disciplines from the medical students to residents to fellows. Dr. Wu has co-supervised one successful masters student and one successful PhD student and continues to supervise as well as participate in committees for other graduate students. She also actively participates in delivering continuing medical education throughout the province.
Dr. Wu is a member of the Resident Training Committee for the Division of Hematology.
Dr. Wu serves as the principal investigator of multiple thrombosis clinical trials and collaborates with basic scientists to investigate coagulation in aging and thrombosis. She created an Alberta-wide linked administrative database to study the epidemiology of VTE. She collaborates with other Canadian thrombosis experts and is the Alberta lead for the Quality and Improvement Platform of the CIHR funded CanVECTOR multicenter thrombosis research network. She has received research funding from several agencies including the University Hospital Foundation, Calgary Clinical Research Fund, CanVECTOR, Canadian Institutes of Health Research, Bayer, Pfizer, and Ottawa Hospital Research Institute.
Her research as co-investigator has been published in numerous peer-reviewed journals that include Journal of Thrombosis and Hemostasis, JAMA Internal Medicine and New England Journal of Medicine.
Hematology, thrombosis, venous thromboembolism
Parker, A., Peterson, E., Lee, AYY., de Wit, C., Carrier M., Polley, G., Tien, J., Wu, C. Risk stratification for the development of venous thromboembolism in hospitalized patients with cancer. J Thromb Haemost., 2018 July;16(7):1321-26
Refaei, M., Fernandes, B., Brandwein, J., Goodyear, MD., Pokhrel, A., Wu, C. Incidence of catheter-related thrombosis in acute leukemia patients: a comparative, retrospective study of safety of peripherally-inserted vs centrally-inserted central venous catheters. Ann Hematol. 2016; 95(12):2057-2064
Fagarasanu, A., Alotaibi, G., Hrimiuc, R., Lee, AYY., Wu, C. Role of extended thromboprophylaxis after abdominal and pelvic surgery in cancer patients: a systematic review and meta-analysis. Ann Surg Onc. 2016; 23(5):1422-30. (also refer to editorial. Ivatury, SJ., Holubar, SD. Just do it: Changing our culture to embrace optimal perioperative venous thromboembolism chemoprophylaxis for abdominal and pelvic cancer patients. Ann Surg Onc. 2016; 23(5):1420-1
Kopolovic, I., Lee, AY., Wu, C. Management and outcomes of cancer-associated venous thromboembolism in patients with concomitant thrombocytopenia: a retrospective cohort study. Ann Hematol. 2015; 94(2):329-336
Carrier, M., Blais, N., Crowther, M., Kavan, P., Le Gal, G., Moodley, O., Shivakumar, S., Tagalakis, V., Wu, C., Lee, A.Y.Y. Treatment algorithm in cancer-associated thrombosis: Canadian Expert Consensus. Curr Onc., 2018 October; 25(5):329-337
Douketis, JD., Spyropoulos, AC., Dunca, J., Carrier, M., Le Gal, Gregoire., Tafur, AJ., Vanassche T., Verhamme, P., Shivakumar, S., Gross, PL., Lee, AYY., Yeo, E., Solymoss, S., Kassis, J., Le Templier, G., Kowalski, S., Blostein, M., Shah, V., MacKay, E., Wu, C., Clark, NP., Bates, SM., Spencer, FA., Arnaoutoglou, E., Coppens, M., Arnold, DM., Caprini JA., Li, N., Moffat, KA., Syed, S, Schulman, S. Perioperative management of patients with atrial fibrillation receiving a direct oral anticoagulant. JAMA Intern Med., 2019 August;179(11):1469-1478
Kearon, C., de Witt, K., Parpia, S, Schulman, S., Afilalo, M., Hirsch, A., Spencer, F., Sharma, S., D’Aragon, F., Deshaies, JF., Le Gal, G., Lazo-Langer, A., Wu, C., Rudd-Scott, L., Bates, SM., Julian, JA. For the PEGeD Study Investigators. Diagnosis of pulmonary embolism with D-dimer adjusted to clinical probability. N Engl J Med., 2019 November;381:2125-34