I am interested in all aspects of cardiac disease and its outcomes, particularly in cardiac rehabilitation and primary and secondary prevention of heart disease. I want to improve cardiac outcomes by developing and supporting a team approach to care; for example, I work with nurses, nurse practitioners and pharmacists in an attempt to implement new approaches to diabetes care, lipid lowering therapies and overall vascular prevention.
General cardiologist Dr. Gabor Gyenes is a graduate of Semmelweis Medical University in Budapest, Hungary where he also completed general internal medicine and cardiology training. Following his clinical training, he obtained a PhD from the Karolinska Institute in Stockholm. Dr. Gyenes was recruited to Mount Sinai Hospital in Toronto and completed an interventional clinical fellowship at the University of Toronto. He was recruited to the University of Alberta in 2001. Over his career he has assumed several leadership roles in the cardiology field and garnered awards for his research and teaching.
Leadership and Collaborations
Dr. Gyenes is cardiac rehabilitation chief for the Edmonton Zone Cardiac Sciences of Alberta Health Services. He is medical director of the Jim Pattison Center for Heart Health (Cardiac Rehabilitation) within the Mazankowski Alberta Heart Institute and director of the Cardiology Patient Triage and Navigation program. Past leadership roles include that of medical director for the cardiology ward and co-director of the Cardiovascular Risk Reduction Clinic.
Dr. Gyenes mentors medical students interested in cardiology, residents, nurse practitioners and international medical graduate students. He presents frequently to medical trainees and professional on grand rounds, and in cardiology practice updates and in continuing medical education sessions. He has won three awards for his teaching excellence.
In his clinical research, Dr. Gyenes studies a range of cardiac topics such as secondary prevention, outcomes of acute coronary syndromes, stable coronary artery disease, radiation-induced heart disease, and cardiac rehabilitation in specific patient populations. His work receives funding from several sources including the Canadian Institutes of Health Research, Heart and Stroke Foundation and the University of Alberta Hospital Foundation. In addition to his involvement with international multi-centre trials, he conducts industry-sponsored clinical trials to assess the effectiveness of specific drugs in treating cardiac conditions.
cardiac rehabilitation, coronary artery disease, lipid lowering drugs, primary and secondary prevention of cardiovascular disease, radiation-induced heart disease
Dr. Gyenes is a widely published author and co-author with research articles and reviews appearing in leading cardiology journals including Circulation; European Journal of Heart Failure; Journal of the Canadian Medical Association; Lancet; New England Journal of Medicine; the International Journal of Radiation, Oncology, Biology and Physics and American Heart Journal. He co-authored the book, 25 Landmark Trials in Cardiology, which is in its fifth edition.
Highlight grants/publications from years prior to 2017:
1. G Gyenes, T Fornander, P Carlens, LE Rutqvist: Morbidity of ischemic heart disease in early breast cancer 15-20 years after adjuvant radiotherapy. Int J Radiation Oncol Biol Phys, 1994;28: 1235-41. (IF: 4.258)
2. G Gyenes, G Gagliardi, I Lax, T Fornander, LE Rutqvist: Evaluation of irradiated heart volumes in stage I breast cancer patients treated with postoperative adjuvant radiotherapy. J. Clin. Oncol., 1997;15:1348-1353. (IF: 18.428)
3. G Gagliardi, I Lax, S Söderström, G Gyenes, LE Rutqvist: Prediction of long-term cardiac mortality after radiotherapy in Stage I breast cancer patients. Radiother Oncol, 1998;46:63-71. (IF: 4.363)
4. MA McDonald, SH Simpson, JA Ezekowitz, G Gyenes, RT Tsuyuki: Angiotensin receptor blockers and risk of myocardial infarction: systematic review. BMJ, 2005;331:873-6. (IF: 17.445)
5. G Gyenes, FM Shrive, MM Graham, WA Ghali, ML Knudtson: The prognostic importance of non-significant left main coronary artery disease in patients undergoing percutaneous coronary intervention. J Am Coll Cardiol, 2006;48:276-80. (IF: 16.503)
6. GT Gyenes, WA Ghali: Should all patients with asymptomatic, but significant (>50%) left main coronary artery stenosis undergo surgical revascularization? Circulation, 2008; 118:422-25. (IF: 14.43).
7. The ONTARGET Investigators: Telmisartan, ramipril, or both in patients at high risk for vascular events. N Engl J Med, 2008;358:1547-59. (IF: 55.873)
8. The TRANSCEND Investigators: Effects of the angiotensin-receptor blocker telmisartan on cardiovascular events in high-risk patients intolerant to angiotensin-converting enzyme inhibitors: a randomised controlled trial. Lancet, 2008;372:1174-83. (IF: 45.217)
9. GT Gyenes, AT Yan, M Tan, RC Welsh, KAA Fox, FR Grondin, JP DeYoung, BF Rose, R Gallo, JM Kornder, GC Wong, and SG Goodman for the GRACE/GRACE2/CANRACE Investigators: Use and timing of coronary angiography and associated in-hospital outcomes in Canadian non-ST segment elevation myocardial infarction patients: insights from the Canadian Global Registry of Acute Coronary Events. Can J Cardiol., 2013; 29:1429-35. (IF: 3.711)
10. R Sharma, C Norris, GT Gyenes, L Wilson, M Senaratne, KR Bainey: Impact of Cardiac Rehabilitation of South Asians with Cardiovascular Disease: Results from The Alberta Provincial Project for Outcomes Assessment in Coronary Heart Disease: (APPROACH) Registry. Can J Cardiol., 2016. 32: S396-S402.
Dr. Gyenes is a general cardiologist with Alberta Health Services at the University of Alberta Hospital who cares for patients with a variety of cardiac problems. He is particularly interested in primary and secondary vascular prevention. In 2010, he co-established a Risk Reduction Clinic for patients with rheumatic disease and developed an algorithm used in the clinic that systematically assessed patient’s cardiac risk factors. He is currently working on developing a new program model for cardiac rehabilitation in the Edmonton region that will maintain high quality of care while decreasing costs.
Doctor of Philosophy
The Effect of Exercise on Hypertension in Chronic Kidney Disease: A Randomized Controlled Trial
- Funding Source: Canadian Institutes of Health Research
- Year Granted: 2018
- Research Role: Co-Investigator