Department of Oncology

Experimental Oncology

Faculty Members are involved in basic scientific research and translational (bench-to-bedside) research. Research interests include:


  1. Molecular analysis of breast cancer, brain tumours, melanoma, pediatric cancers and blood cancers
  2. Mechanisms underlying the repair of DNA damage caused by ionizing radiation and chemotherapeutic drugs
  3. Cell adhesion, cell migration and metastatic spread
  4. Epigenetics of cancer
  5. Tumour suppressor genes
  6. Tumour targeting viruses as cancer therapeutic agents
  7. Computational biology approaches to drug discovery
  8. Cell cycle regulation
  9. Membrane transporters and their role in drug transport and resistance


Possible areas of graduate research include:

Dr. Vickie Baracos  

Muscle atrophy in cancer associated cachexia 


Dr. Kristi Baker

Anti-tumor immunity; genetic instability; colorectal cancer



Dr. Gordon Chan

Mitotic cell cycle checkpoint and cancer 


Dr. YangXin Fu

Signaling pathways and gene regulation in ovarian cancer and therapeutics


Dr. Armin Gamper

DNA damage response: radiation biology



Dr. Roseline Godbout

Cancer as a developmental disease; retinoblastoma; brain tumors



Dr. Michael Hendzel

Nuclear components; DNA damage response; chromatin-based epigenetic mechanisms



Dr. Mary Hitt

Oncolytic viruses; adenovirus replication; gene regulation; RNA interference; gene therapy


Dr. Ismail Ismail

Targeting the DNA damage response in B cell malignancies


Dr. Piyush Kumar 

Development of Molecular Theranostic (Therapy+Diagnostic) Agents For Cancer Diseases



Dr. John Lewis

Translational prostate cancer research; nanoparticles, novel therapeutics, in vivo imaging



Dr. David Murray

DNA repair in the response to anti-cancer agents; prediction of patient response to therapy


Dr. Manijeh Pasdar

Molecular mechanisms of adhesion-mediated signaling during cell growth and oncogenesis


Dr. Lynne Postovit

Environmental control of normal and cancer stem cell plasticity


Dr. Wilson Roa

Nono-carrier platforms for therapeutic applications; image guided radiotherapy


Dr. Michael Sawyer

Cell biology, cell signaling and cancer, drug transporters


Dr. Ralf Schirrmacher

Radiopharmaceutical Chemistry, development of PET imaging agents for neuro- and cancer imaging, medicinal chemistry and drug development



Dr. Jack Tuszynski

Computational biophysics; rational drug design; pharmacokinetics


Dr. Alan Underhill

Transcription factors in melanoma; gene regulation & epigenetics


Dr. Michael Weinfeld

Detection and repair of DNA damage


Dr. Frank Wuest

Probe development for molecular imaging of cancer