Gairdner Symposium 2017


DAY 1

 

8:30

Welcome: Opening remarks

Session 1:

Protein misfolding and proteostatic mechanisms

9:00 - 9:45

Arthur Horwich, Yale University
Protein Folding, Misfolding, and Spread

9:45 - 10:30

Richard Morimoto, Northwestern University
The Stress of Molecular Aging on Cellular Health and Longevity

10:30 - 10:45

Health Break

10:45 - 11:30

David Rubinsztein, Cambridge University Autophagy and neurodegeneration

11:30 - 12:15

David Westaway, University of Alberta
Tracking early events in genetic forms of prion disease and 4-repeat tauopathy

12:15 - 13:30

Lunch & Poster Viewing

Session 2:

From RNA to cell death

13:30 - 14:15

J. Paul Taylor, St. Jude’s Research Hospital
Dynamic RNA-protein assemblies in ALS and related disease

14:15 - 15:00

Phillip Barker, University of British Columbia, Okanagen
Molecular Mechanisms Driving Axon and Dendrite Remodeling

15:00 - 15:30

Health Break

15:30 - 16:15

Jean-Pierre Julien, Université Laval
From pathophysiology of ALS to development of new therapeutics

16:15 - 17:00

Jack Jhamandas, University of Alberta
The amylin receptor: a novel therapeutic target for Alzheimer’s disease

17:00 - 18:30

Posters

Speakers Dinner

TBA


DAY 2

 

8:30

Welcome: Opening remarks

Session 3:

Calcium and glutamate homeostasis/mechanisms of cell death

9:00 - 9:45

Hilmar Bading, Heidelberg The NMDA receptor signaling paradox: neuroadaptation versus neurodegeneration

9:45 - 10:30

Stuart Lipton, The Scripps Research Institute Protecting Synapses in Alzheimer’s Disease:  An Alternative Approach to Disease-Modifying Therapy

10:30 - 10:45

Health Break

10:45 - 11:30

Lynn A. Raymond, University of British Columbia Synaptic changes preceding neurodegeneration in Huntington’s disease: Targets for therapeutic development

11:30 - 12:15

Jeffrey D. Rothstein, Johns Hopkins University
Nuclear transport and nuclear pores: a defect common to neurodegeneration

12:15 - 13:30

Lunch & Poster Viewing

Session 4:

Neuroinflammatory mechanisms of cell death and axonal injury

13:30 - 14:15

Lorraine V. Kalia, University of Toronto
Modelling alpha-synuclein-mediated neurodegeneration

14:15 - 15:00

Bruce D. Trapp, Cleveland Clinic
Neurodegeneration and Demyelination are Independent Events in MS

15:00 - 15:30

Health Break

15:30 - 16:15

Alexandre Prat, Université de Montreal
Mechanisms of Blood Brain Barrier disruption in MS

16:15 - 17:00

V. Wee Yong, University of Calgary
Harnessing the benefits of inflammation for CNS recovery

17:00 - 18:30

Posters

18:30

Reception