Articular Cartilage Research Group

Articular Cartilage Research group:

New protocols to cryopreserve different sizes of articular cartilage for future transplantation
Other joint reconstruction relate research
Example from Ron Moore's group - Urology
Kidney Oncology & Transplantation Research Group:
New therapies to reduce the need to remove urological organs, and clinical analysis of kidney transplantation

Dr. Nadr M Jomha

Nadr Jomha, BMSc, MD, MSc, FRCS(C), PhD is a Professor and Director of Orthopaedic Research in the Division of Orthopaedic Surgery in the Faculty of Medicine and Dentistry.

Dr. Jomha completed fellowships in Knee, Foot and Ankle surgery, and since 1998 has established his current clinical Orthopaedic practice in trauma surgery at the level one trauma center and elective lower extremity reconstructive surgery. His research interest includes Orthopaedic Surgery, Joint Tissue Regeneration and Cryobiology.

Research Keywords: Cryopreservation, 3D modelling, Additives, Animal Model, Articular Cartilage, Cadaveric Model, Cartilage Implant, Microscopy, Cell Culture, Hypoxia, Joint Regeneration, Joint Sparing, Meniscus, Metatarsal-Phalangeal Joint, Orthopaedic Surgery, Osteoarthritis, Prevention, Prosthesis, Prosthetic Replacement, Regeneration, Scaffold, Scaling, Talar Body Replacement, Talar Symmetry, Talus, Synthetic Prosthesis, Tissue Engineering, Titanium Implant, Transplantation.

Conferences: ORS, ICRS, Society for Cryobiology, Extreme Cryo, Alberta BME Conference

The cryobiology lab is a world leader in the cryopreservation of human articular cartilage with a patented protocol to successfully vitrify intact human articular cartilage and continues to work towards clinical translation. Dr. Jomha's labs have participated in research from the bench to animal models. Dr. Jomha is a past president of the Canadian Orthopaedic Research Society and has research connections across Canada.

Current Projects

  1. Vitrification of Articular Cartilage in Human and Pigs -
    This research focuses on the cold preservation of joint cartilage for the purpose of transplantation.
  2. Effect of ice recrystallization inhibitors on cryopreservation of articular cartilage -
    This research investigates methods of decreasing ice formation during the cooling processes.
  3. Gene Expression Profiling of Combined Effect of Hypoxia and Mechanical Stress on Engineered Meniscus -
    This research investigates the effects of low oxygen environments and physical stresses on a meniscus implant created in the lab.
  4. Talar bone dimensions and generic prosthesis -
    This research is direct towards the development of a talar bone replacement prosthesis for severely damaged talar bones.
  5. Engineering Biomimetic Gene Activated Matrices for Bone Tissue Regeneration -
    This research investigates how to generate new bone formation when bones do not heal.

Collaborations (national, international & industrial)

University of Ottawa

Current Opportunities


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