Publications

Follow our lab blog on an siRNA screen for ubiquitin ligases and deubiquitylation enzymes that modify cellular responses to TNF.

  1. Schindler, A., and Foley, E. Hexokinase 1 blocks apoptotic signals at the mitochondria. Cellular Signalling. 2013 25: 2685-2692. PDF
  2. Mereniuk, T.R., El Gendy, M.A.M., Mendes-Pereira, A.M., Lord, C.J., Ghosh, S., R., Foley, E., Unsworth, A., and Weinfeld M. Synthetic lethal targeting of PTEN-deficient cancers using selective disruption of polynucleotide kinase/phosphatase. Molecular Cancer Therapeutics. 2013 12:2135-2144. PDF
  3. Parsons, D.B., and Foley, E. The Drosophila PDGF and VEGF-receptor related (Pvr) pathway controls hemocyte viability and epithelial permeability to invasive hemocytes. Journal of Biological Chemistry. 2013 288(28): 20173-83. PDF
  4. Mereniuk, T.R., Maranchuk, R., Schindler, A;, Penner, J.C., Freschauf, G.K., Hegazy, S., Lai, R., Foley, E., and Weinfeld, M. Genetic screening for synthetic lethal partners of polynucleotide kinase/phosphatase: potential for targeting SHP-1 depleted cancers. Cancer Research. 2012 72(22):5934-44. PDF
  5. Bond, D., and Foley, E. Autocrine PDGF- VEGF- Receptor Related (Pvr) Pathway Activity Controls Intestinal Stem Cell Proliferation in the Adult Drosophila midgut. Journal of Biologcial Chemistry. 2012. 287(33): 27359-70. PDF
  6. Guntermann, S., and Foley, E. Dredd is an essential component of the c-Jun N-terminal Kinase pathway in the Drosophila IMD-dependent immune response. Journal of Biological Chemistry. 2011. 286(35): 30284-94. PDF
  7. Schindler, A., and Foley, E. Hexokinase I protects from Tumor Necrosis Factor induced apoptosis. Cellular Signaling. 2010. 22(9): 1330-1340.
  8. Hong, C., Duit, S., Jalonen, P., Out, R., Scheer, L., Boyadjian, R., Rodenburg, K., Foley, E., Korhonen, L., Lindholm, D., Nimph, J., van Berkel, T., Tontonoz, P., and Zelcer, N. The E3-ubiquitin ligase IDOL induces the degradation of the low-density lipoprotein receptor family members VLDLR and ApoER2. Journal of Biological Chemistry. 2010. 285(26): 19720-6. PDF_button
  9. Parsons, B., Schindler, A., Evans, D.H., and Foley, E. The comparative efficiency of pooled and single siRNAs in a systematic RNAi screen. PLoS ONE. 2009 4(12): e8471. PDF_button
  10. Bond, D., and Foley, E. A quantitative RNAi screen for JNK modifiers identifies Pvr as a novel regulator of Drosophila immune signaling. PLoS Pathogens. 2009 5(11): e1000655. PDF_button
  11. Guntermann, S., Primrose, D., and Foley, E. Dnr1-Dependent Regulation of the Drosophila Immune Deficiency Signaling Pathway. Dev Comp Immunol. 2009 33(1): 127-134. PDF_button
  12. Bond, D*., Primrose, D*., and Foley, E. Quantitative Evaluation of Signaling Events in Drosophila S2 cells. (*authors contributed equally). Biological Procedures Online. 2008 4(10): 20-8. PDF_button
  13. Primrose, D., Chaudhry, S., Johnson, G., Hrdlicka, A., Schindler, A., Tran, D., and Foley, E. Dnr1 Interacts with the Drosophila Initiator Caspases Dredd and Dronc. J Cell Sci. 2007 1;120(Pt 7): 1189-99. Epub 2007 Mar 6. PDF_button
  14. Saleh, M.C., van Rij, R., Hekele, A., Gillis, A., Foley, E., O'Farrell, P.H. and Andino, R. The endocytic pathway mediates cell entry of dsRNA to induce RNAi silencing. Nat Cell Biol. 2006 8(8): 793-802. PDF_button
  15. Stroschein, S., Foley, E., O’Farrell, P.H., and Johnson, A.D. Identification of Drosophila gene products required for phagocytosis of Candida albicans. PLoS Biology. 2006 4(1): e4. Epub 2005 Dec 20. PDF_button
  16. Echard, A.*, Hickson, G.*, Foley, E., and O’Farrell, P.H. Terminal Cytokinesis Events Uncovered After an RNAi Screen. (*authors contributed equally) Curr Biol 2004 14(18): 1685-1693. PDF_button
  17. Foley, E., and O’Farrell, P.H. Functional Dissection of an Innate Immune Response by a Genome-Wide RNAi Screen. PLoS Biol 2004 2(8): E203 1091-1106. PDF_button
  18. Foley, E., and O’Farrell, P.H. Nitric Oxide Contributes to Induction of Innate Immune Responses to Gram-Negative Bacteria in Drosophila. Genes & Dev 2003 17(1): 115-125. PDF_button
  19. Foley, E., and Sprenger, F. The Cyclin-Dependent Kinase Inhibitor Roughex is Involved in Mitotic Exit in Drosophila. Curr Biol 2001 11(3): 151-160. PDF_button
  20. Foley, E., and Sprenger, F. Cyclins: Growing Pains for Drosophila. Curr Biol 2000 10(18): R665-R667. PDF_button
  21. Foley, E., O'Farrell, P. H. and Sprenger, F. Rux is a Cyclin-Dependent Kinase Inhibitor (CKI) Specific for Mitotic Cyclin-Cdk Complexes. Curr Biol 1999 9(23): 1392-1402. PDF_button