The BME 600 seminar series is an opportunity to practice the presentation skills BME graduate students will need for the defense of their thesis, or for presentation of their research at scientific meetings. It is also a forum where you will learn to critically review the scientific and presentation skills of your peers.
Next Upcoming Seminar:
Date: 2019 November 20
NOTICE TO ALL BME 600 STUDENTS: The Access Outreach Team on Campus will be visiting after the November 6th class to discuss student resources.
Time: Noon - 1PM
Location: ECHA L1-220
Presentation Topic: “Phage display derived peptide for removal of carbamylated protein”
Presenter: Yuhao Ma, Dept. of Biomedical Engineering
With a lot of complications derived from chronic kidney disease (CKD), modern hemodialysis plays a very limited role as kidney substitute. Half of identified 150 uremic toxins were found to be protein bounded and cannot be efficiently cleared through hemodialysis, no matter what its flux or dialysis strategy are. Protein carbamylation is a post-translational modification that occurs as a result of urea degradation and is an irreversible process in vivo. Carbamylation of proteins have been linked to an increasing number of diseases, including: cataract formation, enhanced extracellular degradation, reduced enzymatic activity, rheumatoid arthritis, athlerosclerosis, and some misfolded protein diseases (ie. Alzheimer’s disease). The goal of our study is to remove carbamylated protein, carbamylated HSA as a model, from blood by using specific peptide combined on a nonfouling surface. The peptide works a binding element for carbamylated HSA, and nonfouling surface is employed to minimize unwanted nonspecific protein adsorption or biofouling. The difference between normal and carbamylated albumin in terms of its structure and nature has been identified. In order to find the specific peptide that targets carbamylated HSA, phage display technique was applied, and several potential peptides was determined and synthesized. The candidate peptides were successfully
immobilized onto nonfouling surface of polymer brushes through surface chemistry. To test the efficacy of each peptide surface, radiolabeling protein adsorption was performed. As a result, the
potential surface with the ability to selectively remove CHSA from normal HSA was identified.
All are welcome!
11-Sept GSA/FGSR/FoMD/BME Orientation Presentations
25-Sept Rajeev Jaundoo
09-Oct Azzam Hazim
16-Oct Diana Valdes Cabrera
23-Oct Ashmita De
6-Nov Christopher Tsui
20-Nov Karan Vats
4-Dec Gitanjali Chhetri
NOTE that it is mandatory for all BME graduate students to attend BME600 seminars (whether registered for the current course, or not). In the event of an unexpected time conflict, please let me know by email that you will not be able to attend.
RTF Table Tennis Tourney April 2018!
Want to play table tennis (ping-pong)?
Want to meet other people from RTF/Imaging Research?
Why not kill 2 birds with 1 stone?
If you're interested, e-mail Prayash and Kevin (or let them know in person)
Update 4 April 2018:
The paddles are here, the table is set, and the nets are waiting!
Tentatively, we are planning the tournament day during the week of April 23-27, but please use our Table Tennis Tourney Doodle Poll to indicate which day works best for you. The tourney bracket will include everyone who signs up.
We will also have a practice session some time prior to the tournament. We will use this to go over the rules, wipe some of the rust off, and make sure everyone is on the same page! Everyone who is interested can fill out the Practice Day Doodle Poll.
Keep a look out for an e-mail next Friday (April 13) confirming the date and time!
Please feel free to forward this to anyone in BME who may not have received it.
Prayash - room 1-086 RTF
Kevin - room 1-113 RTF