The BME Seminar Series features presentations surrounding the field of Biomedical Engineering.
Next Upcoming Seminar:
Date: 2018 November 28
Time: Noon - 1PM
Location: 1-075 RTF
Presentation Topic: Targeting the Senescence-Associated Secretory Phenotype: The profound effects of natural molecules on inflammation produced by senescent cells
Presenter: Kevin Perrott, PhD Student, Dept. of Biomedical Engineering
Natural compounds from fruits and vegetables such apigenin (4',5,7,-trihydroxyflavone) have been shown to have pleotropic effects able to attenuate the inflammation associated with many chronic diseases of aging. Senescent cells-stressed cells that accumulate with age in mammals-display a pro-inflammatory senescence-associated secretory phenotype (SASP) that can drive or exacerbate several age-related pathologies, including cancer. This work examines the effects and mechanisms of apigenin and other natural compounds on senescence and the SASP looking at the role these natural compounds could play in reducing tumorigenesis.
All are welcome!
The BME Seminar Series features presentations by current graduate students as part of the BME 600A/B courses (Fall/Winter terms). Each of the seminars offers a glimpse into biomedical research taking place at our university.
Details about the next series will be posted soon!
Title: 3-Dimensional Glial Cell Cultures for High-Throughput Assessment of Neuroinflammation
Speaker: Christopher Tsui
Date: Wednesday, Dec. 5, 2018
Time: Noon to 1:00 PM
Venue: ECHA L1-220
In the central nervous system, damage resulting from events such as stroke, traumatic brain injury, or implantation of electrodes or other biomaterials will typically elicit a sustained inflammatory response that includes gliosis, cell death, and glial scar formation that can exacerbate injury and prevent healthy recovery of affected tissue. Implicated in the inflammatory response are glial cells - the regulatory and immune cells of the central nervous system. While ubiquitous 2-dimensional cell cultures are a reductionist and high-throughput means of assessing glial cell reactivity to a wide range of stimuli, 3-dimensional cell cultures build on this concept by offering a more physiologically relevant environment to cells compared to a planar substrate. We make use of photocrosslinked methacrylated hyaluronic acid (HAMA) hydrogels which offer a reproducible means of housing primary glial cells (microglia, astrocytes, oligodendrocytes) and can evaluate their reactivity in a 3-dimensional in vitro environment in response to different injuries. HAMA hydrogels are advantageous because hyaluronic acid, the constituent material, is a natural component of nervous tissue and the macromer weight fraction of hyaluronic acid in a hydrogel mix can be tuned to approximate the mechanical properties of different types of tissue. Previously published results on the synthesis and characterization of the HAMA hydrogels will be presented, along with current work highlighting the versatility of the hydrogels in modelling different types of injury.
All are welcome!
RTF Table Tennis Tourney April 2018!
Want to play table tennis (ping-pong)?
Want to meet other people from RTF/Imaging Research?
Why not kill 2 birds with 1 stone?
If you're interested, e-mail Prayash and Kevin (or let them know in person)
Update 4 April 2018:
The paddles are here, the table is set, and the nets are waiting!
Tentatively, we are planning the tournament day during the week of April 23-27, but please use our Table Tennis Tourney Doodle Poll to indicate which day works best for you. The tourney bracket will include everyone who signs up.
We will also have a practice session some time prior to the tournament. We will use this to go over the rules, wipe some of the rust off, and make sure everyone is on the same page! Everyone who is interested can fill out the Practice Day Doodle Poll.
Keep a look out for an e-mail next Friday (April 13) confirming the date and time!
Please feel free to forward this to anyone in BME who may not have received it.
Prayash - room 1-086 RTF
Kevin - room 1-113 RTF