The BME 600 seminar series is an opportunity to practice the presentation skills BME graduate students will need for the defense of their thesis, or for presentation of their research at scientific meetings. It is also a forum where you will learn to critically review the scientific and presentation skills of your peers.
Next Upcoming Seminar:
Date: 2020 January 22
Time: Noon - 1PM
Location: ECHA L1-220
Presentation Topic: “Myelin Water Imaging in MRI"
Presenter: Nima Mehdizadeh, Dept. of Biomedical Engineering
Myelin is a multilayer stack of uniformly thick membranes wrapped around specific nerve fibers, and enables fast and efficient transduction of electrical signals in the nervous system. De-myelination or myelin loss might hinder brain function and has been associated with neurological diseases such as MS. Tracking myelin content (de/re-myelination) is crucial for diagnosis and treatment of patients with neurodegenerative diseases. MRI is medical imaging technique that has been proven to be valuable in detection of lesions and tracking myelin content. Due to its non-invasive nature, MRI can be used in long term studies to track treatment effects in demyelinated lesions.
There are several methods to measure myelin content using MRI, such as magnetization transfer, VisTA, and etc. We will explore multi-exponential analysis of multi-echo scans, which is a general term for quantitative methods that will provide information about the distribution of transversal relaxation parameter within each voxel; which is then used to acquire the ratio of water trapped between myelin sheaths, to the total water in the voxel. In literature, this ratio is defined as Myelin Water Fraction (MWF). It has been histologically shown that MWF is a good indicator of myelin content in the brain and there is a high correlation between MWF and actual myelin content. Usually, calculations in multi- exponential analyses are done using voxel based algorithms that are effected by noise and generate relatively noisy MWF maps, but recently there has been some multi-voxel based algorithms developed that impose a spatial regularization on the multi-exponential analysis. which will produce smoother MWF maps.
All are welcome!
Wednesday, January 8, 2020 - Welcome to new students & Creating scientific and 3-minute thesis presentations
Wednesday, January 22, 2020
Wednesday, February 5, 2020 - 3-minute thesis competition
Wednesday, February 12, 2020 - 3-minute thesis competition
Wednesday, February 26, 2020
Wednesday, March 11, 2020
Wednesday, March 25, 2020
Wednesday, April 8, 2020
NOTE that it is mandatory for all BME graduate students to attend BME600 seminars (whether registered for the current course, or not). In the event of an unexpected time conflict, please let me know by email that you will not be able to attend.
BME 2019 Celebrate the Season Potluck!
Date: 2019 December 5, Thursday
Location: 1-075 RTF
Time: Noon to... whenever!
Obligation: Please bring a (hot) food dish!
Contact: Kevin Solar@ualberta.ca