The BME Seminar Series features presentations surrounding the field of Biomedical Engineering.
Next Upcoming Seminar:
Date: 2018 November 28
Time: Noon - 1PM
Location: 1-075 RTF
Presentation Topic: Targeting the Senescence-Associated Secretory Phenotype: The profound effects of natural molecules on inflammation produced by senescent cells
Presenter: Kevin Perrott, PhD Student, Dept. of Biomedical Engineering
Natural compounds from fruits and vegetables such apigenin (4',5,7,-trihydroxyflavone) have been shown to have pleotropic effects able to attenuate the inflammation associated with many chronic diseases of aging. Senescent cells-stressed cells that accumulate with age in mammals-display a pro-inflammatory senescence-associated secretory phenotype (SASP) that can drive or exacerbate several age-related pathologies, including cancer. This work examines the effects and mechanisms of apigenin and other natural compounds on senescence and the SASP looking at the role these natural compounds could play in reducing tumorigenesis.
All are welcome!
The BME Seminar Series features presentations by current graduate students as part of the BME 600A/B courses (Fall/Winter terms). Each of the seminars offers a glimpse into biomedical research taking place at our university.
Details about the next series will be posted soon!
Title: High Resolution Diffusion MRI of the Hippocampus Reveals Heterogenous Development across the Head, Body, and Tail Through Childhood and Adolescence
Speaker: Kevin G. Solar
Date: Wednesday, Feb 20, 2019
Time: Noon to 1:00 PM
Venue: ECHA L1-220
The hippocampus is a critical structure for learning and memory, but it is difficult to image given its small size and complex internal architecture. Most hippocampal studies in typical childhood/adolescent development focus on whole/subfield volume or external shape analysis on 3D T1-weighted images. Diffusion tensor imaging (DTI) can provide complementary measures on hippocampal microstructure, but very few studies have focused on its development, and they have been of very low spatial resolution. The purpose of this study was to use high resolution DTI to evaluate age-related changes of the hippocampus head, body and tail in healthy children to young adults. High resolution DTI revealed regional-specificity in microstructural development of the healthy human hippocampus over 6-20 years. The whole structure, head, body, and tail were visualized and segmented directly on mean diffusion-weighted images. Whole-structure analyses showed age-related higher fractional anisotropy (FA) and lower mean diffusivity (MD), and substructure analysis revealed that these associations were strongest in the head – a finding corroborated by prior shape analyses showing greater expansion in the hippocampal head during development. This regional-specificity may reflect hippocampal neurogenesis and myelination in coherence with the high concentration of connections that form at the head from childhood into adulthood.
All are welcome!
2019 March 6 - Graham Little
2019 March 20 - Nashwan Naji
2019 April 3 - Aida Valevicius
RTF Table Tennis Tourney April 2018!
Want to play table tennis (ping-pong)?
Want to meet other people from RTF/Imaging Research?
Why not kill 2 birds with 1 stone?
If you're interested, e-mail Prayash and Kevin (or let them know in person)
Update 4 April 2018:
The paddles are here, the table is set, and the nets are waiting!
Tentatively, we are planning the tournament day during the week of April 23-27, but please use our Table Tennis Tourney Doodle Poll to indicate which day works best for you. The tourney bracket will include everyone who signs up.
We will also have a practice session some time prior to the tournament. We will use this to go over the rules, wipe some of the rust off, and make sure everyone is on the same page! Everyone who is interested can fill out the Practice Day Doodle Poll.
Keep a look out for an e-mail next Friday (April 13) confirming the date and time!
Please feel free to forward this to anyone in BME who may not have received it.
Prayash - room 1-086 RTF
Kevin - room 1-113 RTF