Graduate Student Excellence
Discover the outstanding achievements of our graduate students in the University of Alberta's Department of Pharmacology! Their research is taking our department from the intersection of health and medicine to the leader in both. We wish to congratulate these future health leaders for all of their accomplishments!
AWARDS
Nayiar Shahid - Dr Edwin E Daniel Graduate Scholarship in Pharmacology (2025)
FIRST AUTHOR PUBLICATIONS
Liye Fang
Zhang Z, Fang L, Furukawa H, Huang A, Kranrod J, Seubert JM, Ito K, Aoki S. Maladaptive role of peridroplet mitochondria during lipophagy disruption in pancreatic cancer. Biochem Biophys Res Commun. 2025 Sep 30;782:152609.
John Monyror
Monyror J, Kadam V, Morales LC, Ordóñez D, Ibanga J, Zaidi AK, McNamara E, Pink D, Stenlund M, Reyes K, Maguire AD, Huang J, Cortez LM, Sim VL, Mok SA, Posse de Chaves E, Sipione S. Gangliosides modulate the secretion of extracellular vesicles and their misfolded protein cargo. Sci Adv. 2025 Sep 19;11(38):eady5212.
PUBLICATIONS
Liye Fang
Yousef A, Fang L, Heidari M, Huang A, Kondraciuk P, Yee KA, Mengel M, Seubert JM. Alterations in mitochondria and cellular senescence in aged sEH null female kidneys. GeroScience 2025.
Sun Q, Wagg CS, Wong N, Wei K, Ketema EB, Zhang L, Fang L, Seubert JM, Lopaschuk GD. Alterations of myocardial ketone metabolism in heart failure with preserved ejection fraction (HFpEF). ESC Heart Fail 2025;12:3179-3182.
Yousef A, Fang L, Heidari M, Kranrod J, Seubert JM. The role of CYP-sEH derived lipid mediators in regulating mitochondrial biology and cellular senescence: implications for the aging heart. Frontiers in Pharmacology 2024;15.
Valencia R, Kranrod JW, Fang L, Soliman AM, Azer B, Clemente-Casares X, Seubert JM. Linoleic acid-derived diol 12,13-DiHOME enhances NLRP3 inflammasome activation in macrophages. The FASEB Journal 2024;38:e23748.
Kranrod JW, Darwesh AM, Bassiouni W, Huang A, Fang L, Korodimas JV, Adebesin AM, Munnuri S, Falck JR, Seubert JM. Cardioprotective Action of a Novel Synthetic 19,20-EDP Analog Is Sirt Dependent. Journal of Cardiovascular Pharmacology 2024;83:105-115.
Yousef A, Sosnowski DK, Fang L, Legaspi RJ, Korodimas J, Lee A, Magor KE, Seubert JM. Cardioprotective response and senescence in aged sEH null female mice exposed to LPS. American Journal of Physiology-Heart and Circulatory Physiology 2024;326:H1366-H1385. Zhang Z, Fang L, Furukawa H, Huang A, Kranrod J, Seubert JM, Ito K, Aoki S. Maladaptive role of peridroplet mitochondria during lipophagy disruption in pancreatic cancer. Biochem Biophys Res Commun. 2025 Sep 30;782:152609.
Thomas Hammond
Kanyo R, Lamothe SM, Hammond TM, Kurata HT. State-dependent regulation of the Kv7.2 channel voltage sensor by QO-58. Br J Pharmacol. 2025 Sep 12. doi: 10.1111/bph.70186. Epub ahead of print. PMID: 40937839.
Friedman TN, Lamothe SM, Maguire AD, Hammond T, Tenorio G, Hilton BJ, Plemel JR, Kurata HT, Kerr BJ. Plasticity of Mouse Dorsal Root Ganglion Neurons by Innate Immune Activation Is Influenced by Electrophysiological Activity. J Neurochem. 2025 Jan;169(1):e16292. doi: 10.1111/jnc.16292
Penalva YCM, Paschkowsky S, Recinto SJ, Duchesne A, Hammond T, Spiegler P, Jansen G, Levet C, Charron F, Freeman M, McKinney RA, Trempe JF, Munter LM. Eta-secretase-like processing of the amyloid precursor protein (APP) by the rhomboid protease RHBDL4. J Biol Chem. 2024 Aug;300(8):107541. doi: 10.1016/j.jbc.2024.107541.
Elodie Nickner
Zumbusch AS, McEachern ELF, Morgan OB, Nickner E, Mogil JS. Normative Preclinical Algesiometry Data on the von Frey and Radiant Heat Paw-Withdrawal Tests: An Analysis of Data from More Than 8,000 Mice Over 20 Years. J Pain. 2024 Jul;25(7):104468. doi: 10.1016/j.jpain.2024.01.333.
Chaudhry LA, Aboud I, Ferland M, Cuillerier NS, Carrier SS, Nickner E, Martel MO, Mogil JS. The direction and magnitude of conditioned pain modulation is dependent on test stimulus intensity in healthy participants but not in those with fibromyalgia. J Pain. 2025 Aug 15;36:105534. doi: 10.1016/j.jpain.2025.105534.
CONFereNCES
Liye Fang
Sexual dimorphism in the cardioprotective effects toward myocardial infarction following genetic deletion of soluble epoxide hydrolase in aged mice.
American Heart Association's Basic Cardiovascular Sciences Scientific Sessions 2025: Advances in Cardiovascular Science: From Discovery to Translation.
Poster Peesentation
Thomas Hammond
PIP2 influences KV7.2 regulation by voltage-sensor targeted drugs.
Biophysical Society 2025
Poster Presentation
John Monyror
Glyco27 – The 27th International Glycoconjugate Symposium, May 25-30th 2025
Poster Presentation