PaulStothard01

Paul Stothard

Professor

Agricultural Life and Environmental Sciences

Agricultural Food and Nutritional Science

About Me

Degree 

PhD, molecular biology and genetics, University of Alberta

Job/Research Area 

Bioinformatics, genomics, and genetics


Research

Genetic basis of important traits in animals - we are using whole-genome sequencing and bioinformatics to understand the genetic basis of production and health traits in animals.


Mechanisms of pathogen resistance and resilience in livestock - we are using information in the form of genotypes, miRNA profiles, and mRNA profiles to understand what makes some individuals less susceptible to infection or better able to tolerate infection.


Genome variation and evolution - we are developing novel tools for visualizing sequence differences among individuals and species, and for predicting the impacts of small- and large-scale sequence variants. We are using these tools to perform detailed comparisons of animal genomes and to find functionally important variants.


Software tools for bacterial genome interpretation - we are creating an expert system to process, analyze, and visualize bacterial genomic sequence data. This system uses high-performance computing to quickly deliver high-quality and comprehensively annotated assemblies. 


Teaching

AN SC 484 - Animal Molecular Biology. Students learn about the major approaches and methodologies of applied molecular biotechnology in animal science, including recently developed methods for genome editing. Selected research papers are presented and discussed in class and students write a term paper.


AFNS 508 - Applied Bioinformatics. Introduction to databases, software tools, and analysis methods used to characterize DNA and protein sequences. Topics include information retrieval from sequence databases, protein function prediction, assessing sequence similarity, biological pathway analysis, measuring gene expression, proteomics, and protein identification.


AN SC 479/AN SC 499 - Integrative Problem Solving Project in Animal Science and Animal Health. Students complete an applied research project that involves writing a proposal, conducting research, performing statistical analyses, preparing a scientific manuscript, and presenting the results in a public forum.