Process Systems Integration Modeling and Optimization of Pharmaceutical

Dr. Marianthi Ierapetritou
University of Delaware

3:30pm - March 11, 2021 Online

Abstract:

The global pharmaceutical industry has been on an growing trend since the early 2000s, enhancing life expectancies and healthcare around the world. As a result, the overall pharmaceutical revenue and sales have steadily been increasing, reaching $967 billions in 2016, with research allocations of $300 billions in drug development and manufacturing. Regulated by government agencies like U.S. Food and Drug Administration (FDA) and European Medicine Agency, drug industry has been traditionally resisted to changes especially related to drug production/manufacturing a trend that has been revised over the last decade to enable more efficient and agile manufacturing technologies and to ensure product quality eliminating drug shortages.

Recent developments towards Industry 4.0 have led to generation of large volume of data for the entire manufacturing cycle that could lead to complete transformation of drug manufacturing. However, what is needed is the development of efficient approaches that are capable to efficiently extract the available information, visualize the state of the system, and help in the decision making.

Process Systems Engineering can play a critical role in this transformation with the development of new modeling frameworks and algorithmic solution approaches. The major challenges to achieve this goal, and highlights of the work that has been performed in our lab in the recent years to address these problems will be covered in the talk.

Biography:

ierapetritou.jpegMarianthi Ierapetritou is the Bob and Jane Gore Centennial Chair Professor in the Department of Chemical and Biomolecular Engineering at University of Delaware. Prior to that she has been a Distinguished Professor in the Department of Chemical and Biochemical Engineering at Rutgers University. During the last year at Rutgers University she led the efforts of the university advancing the careers in STEM for women at Rutgers as an Associate Vice President of the University.