Trial Endpoints

Primary Outcome
The length of ICU stay as measured in hours.

Secondary Outcomes

  1. Total and Post-ICU hospital length of stay in hours
  2. Duration of IV vasopressor support in hours
  3. 90-day all-cause mortality
  4. Rates of ICU re-admission
  5. Rate of re-initiation of IV vasopressor

Tertiary Outcomes

  1. ICU costs
  2. Hospital costs
  3. Total healthcare costs
  4. Cost-effectiveness

Safety Endpoints

  1. Adverse drug reactions (ADR)
  2. Serious adverse drug reactions (SADRs)
  3. Suspected unexpected serious adverse reactions (SUSARs)