Faculty
Chris Bleackley | Mechanisms of cell-mediated cytotoxicity and apoptosis |
David Brindley | Targeting the autotaxin-lysophosphatidate-inflammatory axis to improve cancer treatment |
Joseph Casey | Membrane Transport in Corneal Blindness |
Richard Fahlman | Discovery of Novel Functions of small RNAs |
Carlos Fernandez-Patron | Biology of matrix metalloproteinases (MMPs) in health and disease |
Larry Fliegel | Regulation of intracellular pH via the Na+/H+ exchanger |
Mark Glover | Mechanisms of regulation of gene expression |
Ing Swie Goping | Investigating mammary gland biology and breast cancer |
Charles Holmes | Regulation of protein phosphatases and phosphorylation |
Olivier Julien | Functional proteomics and protease biology |
Joanne Lemieux | Structural studies of membrane proteins associated with disease states |
Bernard Lemire | The mitochondrial respiratory chain in disease and in aging |
Andrew MacMillan | Chemical and biochemical mechanisms of RNA processing |
Marek Michalak | Endoplasmic reticulum in health and disease |
Sue-Ann Mok | Deciphering the functional architecture of molecular chaperone networks |
Michael Overduin | Structural biology of signaling and trafficking |
Michael Schultz | Metabolic programming in vertebrate cells |
Leo Spyracopoulos | Structure and function of proteins involved in the protein ubiquitination pathway |
David Stuart | Mechanisms of regulation of cell division |
Brian Sykes | Structure, function and dynamics of muscle, prion, membrane, and antifreeze proteins |
Nicolas Touret | Molecular Cell Biology of Innate Immune Receptors |
Holger Wille | Structural investigations of infectious prions and other misfolded proteins |
Howard Young | Regulation of calcium transport in heart disease |
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Emeriti |
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Michael Ellison | Mechanisms of cellular regulation |
Michael James | Three-dimensional structure of proteins; hydrolytic mechanisms of proteinases |
Cyril Kay | Muscle contraction/relaxation: Protein de novo design |
Ronald MacElhaney | Roles of lipids in the structure and function of biological membranes |
Paul Scott |
Structure and function of extracellular matrix macromolecules |
Jim Stone | Neoplastic transformation of cultured cells by dominant oncogenes |
Dennis Vance | Molecular and cell biology of phospholipid biosynthesis and function |
Joel Weiner | Membrane protein structure and bioenergetics |
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Adjunct |
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Rosalind Godbout | Regulation of gene expression in the developing retina and in retinoblastoma |
Peter Hwang | (1) Developing solution NMR for large protein complexes and membrane proteins. (2)Targeting the cardiac troponin complex to understand and treat heart failure. |
Rene Jacobs | Understand the complex interactions involved in the etiology of obesity, Diabetes and other chronic diseases |
Liang Li | Analytical mass spectrometry (MS) for metabolomics and proteomics |
Luis Schang | Protein kinases and other cellular factors in the replication and pathogenesis of viruses and prions |
Lorne Tyrrell | Study of hepatitis B virus (HBV) and hepatitis C virus (HCV) |
David Westaway | The use of genetically engineered "transgenic" mice to recreate and understand human neurologic disorders |
Dawei Zhang | Regulation of cholesterol homeostasis |
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