Dr Po-Yin Cheung
MBBS, University of Hong Kong, 1985
PhD (Pharmacology), University of Alberta, 1998
FRCP, Canada & Edinburgh, 2001 & 2002
Teaching: PMCOL425, PMCOL515, PMCOL525
Research: Novel interventions to improve the recovery from neonatal asphyxia
Research Interests / Laboratory Techniques
Cardiovascular Physiology and Pharmacology During Hypoxia and Reoxygenation in Newborns. My research consists of both clinical as well as basic science studies in the neonate. I investigate the effects of novel interventions in critically ill neonates and the long-term outcome in early childhood. Newborn piglet is the animal model used in the laboratory for basic science studies. The current focus of the Neonatal Sciences Laboratory is on the effects of hypoxia-reoxygenation injury and the actions of inotrope and other cardiovascular supportive drugs in systemic and regional circulations and platelet functions.
Selected Recent Publications
Solevåg AL, Schmölzer GM, Nakstad B, Saugstad OD and Cheung PY. (2017) Association between Brain and Kidney Near-Infrared Spectroscopy and Early Postresuscitation Mortality in Asphyxiated Newborn Piglets. Neonatology 112(1):80-86. PMID: 28380491.
Huang H, Cheung PY, O'Reilly M, van Os S, Solevåg AL, Aziz K, Schmölzer GM. (2017) Impact of Changing Clinical Practices on Early Blood Gas Analyses in Very Preterm Infants and Their Associated Inpatient Outcomes. Front Pediatr 5:11. PMID: 28243581.
Solevåg AL, Haemmerle E, van Os S, Bach KP, Cheung PY and Schmölzer GM. (2016) A Novel Prototype Neonatal Resuscitator That Controls Tidal Volume and Ventilation Rate: A Comparative Study of Mask Ventilation in a Newborn Manikin. Front Pediatr 4:129. PMID: 27965949.
Phillipos E, Solevåg AL, Aziz K, van Os S, Pichler G, O'Reilly M, Cheung PY and Schmölzer GM. (2017) Oxygen Saturation and Heart Rate Ranges in Very Preterm Infants Requiring Respiratory Support at Birth. J Pediatr 182:41-46.e2. PMID: 27939259.
Solevåg AL, Lee TF, Lu M, Schmölzer GM and Cheung PY. (2017) Tidal volume delivery during continuous chest compressions and sustained inflation. Arch Dis Child Fetal Neonatal Ed 102(1):F85-F87. PMID: 27566670.
Svan Os S, Cheung PY, Kushniruk K, O'Reilly M, Aziz K and Schmölzer GM. (2016) Assessment of endotracheal tube placement in newborn infants: a randomized controlled trial. J Perinatol 36(9):796. PMID: 27562185.
Pinto M, Solevåg AL, OʼReilly M, Aziz K, Cheung PY and Schmölzer GM. (2017) Evidence on Adrenaline Use in Resuscitation and Its Relevance to Newborn Infants: A Non-Systematic Review. Neonatology 111(1):37-44. PMID: 27522216.
Solevåg AL, Schmölzer GM, O'Reilly M, Lu M, Lee TF, Hornberger LK, Nakstad B and Cheung PY. (2016) Myocardial perfusion and oxidative stress after 21% vs. 100% oxygen ventilation and uninterrupted chest compressions in severely asphyxiated piglets. Resuscitation 106:7-13. PMID: 27344929.
Li ES, Cheung PY, Lee TF, Lu M, O'Reilly M and Schmölzer GM. (2016) Return of spontaneous Circulation Is Not Affected by Different Chest Compression Rates Superimposed with Sustained Inflations during Cardiopulmonary Resuscitation in Newborn Piglets. PLoS One 11(6):e0157249. PMID: 27304210.
Solevåg AL, Schmölzer GM and Cheung PY. (2016) Right Ventricular Myocardial Ischemia with Arrhythmia in an Asphyxiated Newborn. AJP Rep 6(2):e203-5. PMID: 27280062.
Solevåg AL and Cheung PY. (2016) Predicting the Outcome of Congenital Diaphragmatic Hernia in a SNAP (Score for Neonatal Acute Physiology). Pediatr Crit Care Med 17(6):570-1. PMID: 27261649.
Pichler-Stachl E, Pichler G, Baik N, Urlesberger B, Alexander A, Urlesberger P, Cheung PY and Schmölzer GM. (2016) Maternal stress after preterm birth: Impact of length of antepartum hospital stay. Women Birth 29(6):e105-e109. PMID: 27156020.
Solevåg AL, Haemmerle E, van Os S, Bach KP, Cheung PY and Schmölzer GM. (2017) Comparison of positive pressure ventilation devices in a newborn manikin. J Matern Fetal Neonatal Med 30(5):595-599. PMID: 27090159.
Cheung PY and Pfeffer SR. (2016) Transport Vesicle Tethering at the Trans Golgi Network: Coiled Coil Proteins in Action. Front Cell Dev Biol 4:18. PMID: 27014693.
Vento M, Schmölzer G, Cheung PY, Finer N, Solevåg AL, Oei JL and Saugstad OD. (2016) What initial oxygen is best for preterm infants in the delivery room?-A response to the 2015 neonatal resuscitation guidelines. Resuscitation 101:e7-8. PMID: 26827713.