Ari Joffe

Ari Joffe, ​MD, FRCPC is a Clinical Professor, Department of Pediatrics, Division of Pediatric Critical Care, University of Alberta. Ari is an attending physician in Pediatric Critical Care Medicine. He has interests in animal ethics [e.g., is it morally permissible to perform harmful animal research? (no)], and the definition of death [e.g., is brain death the state of death of the human organism? (no), and is the donation after circulatory death donor dead when organ removal starts? (no)]. His other research interests are in long-term outcomes in children having complex interventions in the pediatric intensive care unit, focusing on potentially modifiable acute care variables that may lead to improved decision making and outcomes. He has published broadly on these topics and others.

Selected Publications

Nostedt, S., & Joffe, A. R. (2022a). Reverse Bayesian implications of p-values reported in critical care randomized trials. Journal of Intensive Care Medicine,

Nostedt, S., & Joffe, A. R. (2022b). Critical care randomized trials demonstrate power failure: a low positive predictive value of findings in the critical care research field. Journal of Intensive Care Medicine.

Joffe, A. R. (2022a). What About the COVID-19 Response? Evidence: Risk, Lockdowns, and Vaccine Mandates. Health Ethics Today, 29(1), 8-12.

Joffe, A. R. (2022b). Response to Editorial Commentary. Health Ethics Today, 29(1), 14-15.

Joffe, A. R., Khaira, G., & deCaen, A. R. (2021). The intractable problems with brain death and possible solutions. Philosophy, Ethics, and Humanities in Medicine,16(11).

Joffe, A. R., Hansen, G., & Tibballs, J. (Summer 2021). The World Brain Death Project: The More You Say It Does Not Make It True. Journal of Clinical Ethics, 32(2), 97-108.

Joffe, A. R. (2021). COVID-19: Rethinking the lockdown groupthink. Frontiers in Public Health, 9.

Joffe, A. R., & Redman, D. (2021a).The SARS-CoV-2 pandemic in high income countries such as Canada: a better way forward without lockdowns. Frontiers in Public Health, 9.

Joffe, A. R., & Redman, D. (2021b). Applying Philosophy, Logic, and Rational Argumentation to the Severe Acute Respiratory Syndrome Coronavirus-2 Pandemic Response. Preprints 2021.

Robertson, C. M. T., Bork, K. T., Tawfik, G., Bond, G. Y., Hendson, L., Dinu, I. A., Khodayari Moez, E., Rebeyka, I. M., Garcia Guerra, G., & Joffe, A. R. (2019). Avoiding furosemide ototoxicity associated with single-ventricle repair in young infants. Pediatric Critical Care Medicine20(4), 350-356.

Hodson, J. Garros, C., Jensen, J., Duff, J. P., Garcia Guerra, G., & Joffe, A. R. (2019). Parental opinions regarding consent for observational research of no or minimal risk in the pediatric intensive care unit. Journal of Intensive Care, 7(60).

Joffe, A. DCDD donors are not dead. (2018). Hastings Center Report, 48(Suppl 4), S29-S32.

Joffe, A. R., Bara, M., Anton, N., & Nobis, N. (2016). Expectations for the methodology and translation of animal research: a survey of the general public, medical students and animal researchers in North America. Alternatives to Laboratory Animals, 44(4), 361-381.

Joffe, A. R., Bara, M., Anton, N., & Nobis, N. (2016). The ethics of animal research: a survey of the public and scientists in North America. BMC Medical Ethics, 17(17).