Nuclear Magnetic Resonance Laboratory

The high resolution Nuclear Magnetic Resonance (NMR) Laboratory is equipped with eight state-of-the-art Agilent liquids spectrometers, ranging from 400 to 700 MHz (9.4 to 16.45 T). Student, staff, research associates and post-doctoral fellows have direct and frequent access to four 400's, two 500's, one 600, and one 700 MHz NMR spectrometers.We are expecting our first multi-dimensional and multi-nuclear 800 MHz NMR spectrometer in spring of 2023.  This new instrument will have both liquids and solids NMR capabilities providing the broadest possible sample range.One of our 500 MHz instruments is outfitted with a 13C specific cryogenically cooled probe for outstanding carbon detection. Our flagship 700 is also equipped with an ultra high sensitivity cryogenically cooled probe optimizing 1H detection, along with a robotic sample handling system. The instruments are accessible 24/7/365 and can be reserved by department members via our web-based reservation system.

All systems are multi-channel instruments capable of shaped pulses for selective excitation, pulsed field gradients and temperature control for acquisition of all modern NMR experiments. One-dimensional experiments for an extremely wide range of nuclei are available (e.g. 1H, 13C, 11B, 31P, and "exotic nuclei" such as 2H, 63Cu, 171Yb, 195Pt, etc.) also special or unusual techniques and variable temperature studies. All highly utilized multi-dimensional experiments such as COSY, ROESY, TOCSY, NOESY, HSQC , HMBC, etc. are available and experiments are pre- or self-optimizing and often available to the end user via a single click in a customized user-friendly computer environment. All spectrometers and data stations are fully networked and highly integrated with each other. Acquired data sets are centrally stored, archived, and can be accessed and processed throughout the Department including via personal computers. All NMR systems utilize the same acquisition and processing software, with many locally developed additions, to ensure the most efficient use of instrument time and enabling the instrument operation with minimal user training.

A small but dedicated staff is present to assist users and maintain the NMR facility. The NMR support group also provides service to researchers who may not be able to perform their own measurements or require special techniques.

Users external to the Department of Chemistry can also access the services of the NMR facility with some fees for cost recovery. Services provided by the NMR support group includes but is not limited to routine experiments, long acquisitions on sample limited solutions, and customized experiments for unique projects.

Three solid state spectrometers (300, 400, and 500 MHz) are located in the solid state NMR research group with a wide range of probes (double- and triple-resonance, MAS, single-crystal etc.). Micro-imaging capabilities are available on the 300 MHz system.