Dr. Sebastian Straube

Professor / Division Director

Department of Medicine

Division of Preventive Medicine
    Contact details are for academic matters only.

About Me

Sebastian Straube holds degrees in Medicine and Physiological Sciences from the University of Oxford (England) where he also did his DPhil (PhD). After clinical work and research at the Oxford Radcliffe Hospitals, Dr. Straube joined the Institute of Occupational, Social and Environmental Medicine at the University Medical Center Göttingen, Germany. Here he completed his Habilitation (German postdoctoral qualification) and his postgraduate medical training in the specialties of Occupational Medicine and Social Medicine. Dr. Straube was an Extraordinary Professor at the University of Göttingen until he took up his current post as Associate Professor in the Division of Preventive Medicine of the University of Alberta in September 2014. He was appointed as Interim Division Director for Preventive Medicine in December 2015 and as Division Director in July 2016. Dr. Straube’s primary research interest is in evidence-based medicine (systematic reviews and meta-analyses).


A number of research projects are ongoing including the following:

Effectiveness and safety of opioid therapy

Funded by the Workers' Compensation Board of Alberta (WCB Alberta) and the Centre for Effective Business Management of Addiction Treatment, this research analyses opioid prescriptions and clinical response in WCB Alberta claimants, supplemented by two overviews of Cochrane Reviews on the efficacy and safety of opioids when these medications are used for chronic non-cancer pain.

This podcast explains the findings of one of the overviews of Cochrane Reviews: http://www.cochrane.org/podcasts/10.1002/14651858.CD012509.pub2

Occupational interventions for the prevention of back pain – overview of systematic reviews and demonstration of knowledge-translation application

Funded by the Alberta Ministry of Labour (OHS Futures research funding program), we are performing an overview of systematic reviews on occupational interventions for the prevention of back pain. This is currently well under way; analyses have been completed and a manuscript for publication has been submitted.

Effectiveness of random drug and alcohol screening as an intervention for occupational injury prevention

Funded by the Alberta Ministry of Labour (OHS Futures research funding program), we are conducting a Cochrane Review on random drug and alcohol screening in the occupational setting. 

Research Keywords

Chronic non-cancer pain, Effectiveness, effects of interventions, Evidence-based medicine, High dose opioids, knee and hip osteoarthritis, Long term use, Meta-analyses, Prescription analysis, randomised controlled trials, reporting in abstracts and full texts, Safety, Systematic review, Systematic Reviews, work-related outcomes