Faculty

Dr. Rachel Khadaroo

Associate Professor

Department of Surgery

Division of General Surgery

About Me

I am a surgeon, critical care medicine specialized, and scientist at the University of Alberta Hospital and an assistant professor in the Division of General Surgery. My clinical interests are in Acute Care Surgery and critical illness.

I earned my Bachelor of Science and Doctor of Medicine at McMaster University in Hamilton, Ontario. My Doctor of Philosophy was achieved in the Surgical Scientist Program at the University of Toronto with my thesis in oxidant-induced lung injury following trauma.

I completed my General Surgery training at the University of Alberta and further specialized in the area of Critical Care Medicine at the University of Toronto.

Degrees & Appointments

MD (McMaster University, Hamilton, Ontario), 

PhD (Experimental Surgery/molecular/cellular biology, University of Toronto)

FRCSC (General Surgery, University of Alberta)

Critical Care Medicine Fellowship (University of Toronto)

Assistant Professor in Department of Surgery (University of Alberta)


Research

Intestinal Ischemia/Reperfusion injury, sepsis, lung injury, innate immunity, inflammatory cell signaling, surgical infection, acute care surgery 

Brief Summary of my Research

My major research interests relate to intestinal injury and the role the intestine has in critical illness, multiple organ dysfunction, and sepsis. To accomplish our goals my laboratory has developed clinically relevant animal and cellular models.  Specifically, my lab is working on:

  1. Understand the cellular and molecular mechanisms whereby intestinal ischemia/reperfusion injury causes distant organ injury and consequent patient morbidity and mortality.
  2. Discovering unique biomarkers to better diagnosis intestinal injury
  3. Examining how these biomarkers act through intracellular signaling leading to an augmented inflammatory response
  4. Validate these biomarkers in a clinical setting and examine the role of acute intestinal ischemia/reperfusion plays in resultant multiple organ dysfunction, acute lung injury, and sepsis

Research Keywords

Animal models, Cell signaling, Gastrointestinal disease, Inflammatory response, Multiple organ dysfunction, Sepsis