Our gene lists are pathogenesis-based transcripts sets (PBTs) that were generated by using Affymetrix Microarrays. The PBTs were defined to represent the major biologic events in cellular graft rejection, cytotoxic T-cell infiltration, interferon-gamma effects and epithelial deterioration. They were derived from experimental mouse kidney transplants, cultured cells and human kidney biopsies.
The Molecular Phenotype of Kidney Transplants. PF Halloran, DG de Freitas, G Einecke, KS Famulski, LG Hidalgo, M Mengel, J Reeve, J Sellares and B Sis. American Journal of Transplantation 2010;10:2215-2222
Fundamental Concepts Regarding Graft Injury and Regeneration: Tissue Injury, Tissue Quality, and Recipient Factors. C Kreepala, KS Famulski and PF Halloran. Textbook of Organ Transplantation, First Edition. Edited by AD Kirk, SJ Knectle, CP Larsen, TC Pearson and JC Madsen. © 2013 John Wiley & Sons, Ltd. Published 2013 by John Wiley & Sons, Ltd., Chapter 10, pp 99-118
Human PBTs: kidney and inflammatory cells
Human PBTs: cardiac injury and cardiac associated; HG U133_2.0_plus arrays
Mouse PBTs; MG 430_2.0 arrays